FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2171010297> ?p ?o ?g. }

• W2171010297 endingPage "523" @default.
• W2171010297 startingPage "499" @default.
• W2171010297 abstract "The rhizomes of Zingiber officinale Roscoe (Zingiberaceae), commonly known as ginger, is one of the most widely used spice and condiment. It is also an integral part of many traditional medicines and has been extensively used in Chinese, Ayurvedic, Tibb-Unani, Srilankan, Arabic, and African traditional medicines, since antiquity, for many unrelated human ailments including common colds, fever, sore throats, vomiting, motion sickness, gastrointestinal complications, indigestion, constipation, arthritis, rheumatism, sprains, muscular aches, pains, cramps, hypertension, dementia, fever, infectious diseases, and helminthiasis. The putative active compounds are nonvolatile pungent principles, namely gingerols, shogaols, paradols, and zingerone. These compounds are some of the extensively studied phytochemicals and account for the antioxidant, anti-inflammatory, antiemetic, and gastroprotective activities. A number of preclinical investigations with a wide variety of assay systems and carcinogens have shown that ginger and its compounds possess chemopreventive and antineoplastic effects. A number of mechanisms have been observed to be involved in the chemopreventive effects of ginger. The cancer preventive activities of ginger are supposed to be mainly due to free radical scavenging, antioxidant pathways, alteration of gene expressions, and induction of apoptosis, all of which contribute towards decrease in tumor initiation, promotion, and progression. This review provides concise information from preclinical studies with both cell culture models and relevant animal studies by focusing on the mechanisms responsible for the chemopreventive action. The conclusion describes directions for future research to establish its activity and utility as a human cancer preventive and therapeutic drug. The above-mentioned mechanisms of ginger seem to be promising for cancer prevention; however, further clinical studies are warranted to assess the efficacy and safety of ginger." @default.
• W2171010297 created "2016-06-24" @default.
• W2171010297 creator A5004060792 @default.
• W2171010297 creator A5015552418 @default.
• W2171010297 creator A5017499221 @default.
• W2171010297 creator A5028012930 @default.
• W2171010297 creator A5039483577 @default.
• W2171010297 creator A5064987034 @default.
• W2171010297 creator A5068403074 @default.
• W2171010297 date "2011-07-01" @default.
• W2171010297 modified "2023-10-10" @default.
• W2171010297 title "Update on the Chemopreventive Effects of Ginger and its Phytochemicals" @default.
• W2171010297 cites W130533916 @default.
• W2171010297 cites W1542158237 @default.
• W2171010297 cites W1965336187 @default.
• W2171010297 cites W1965734230 @default.
• W2171010297 cites W1967389878 @default.
• W2171010297 cites W1968609146 @default.
• W2171010297 cites W1970961751 @default.
• W2171010297 cites W1973196036 @default.
• W2171010297 cites W1973534046 @default.
• W2171010297 cites W1974199974 @default.
• W2171010297 cites W1974317527 @default.
• W2171010297 cites W1975455729 @default.
• W2171010297 cites W1976404058 @default.
• W2171010297 cites W1976618621 @default.
• W2171010297 cites W1977268963 @default.
• W2171010297 cites W1978915215 @default.
• W2171010297 cites W1981598406 @default.
• W2171010297 cites W1981714984 @default.
• W2171010297 cites W1981913116 @default.
• W2171010297 cites W1982523260 @default.
• W2171010297 cites W1983991479 @default.
• W2171010297 cites W1984543805 @default.
• W2171010297 cites W1986627544 @default.
• W2171010297 cites W1987741979 @default.
• W2171010297 cites W1990913856 @default.
• W2171010297 cites W1991991878 @default.
• W2171010297 cites W1993839684 @default.
• W2171010297 cites W1994916345 @default.
• W2171010297 cites W1995847442 @default.
• W2171010297 cites W1996775799 @default.
• W2171010297 cites W1996877920 @default.
• W2171010297 cites W1997805494 @default.
• W2171010297 cites W1998801635 @default.
• W2171010297 cites W2001342571 @default.
• W2171010297 cites W2002801265 @default.
• W2171010297 cites W2004585767 @default.
• W2171010297 cites W2005451967 @default.
• W2171010297 cites W2006452078 @default.
• W2171010297 cites W2006978420 @default.
• W2171010297 cites W2007499788 @default.
• W2171010297 cites W2008398034 @default.
• W2171010297 cites W2009267289 @default.
• W2171010297 cites W2013028549 @default.
• W2171010297 cites W2014992862 @default.
• W2171010297 cites W2015104147 @default.
• W2171010297 cites W2015509648 @default.
• W2171010297 cites W2017767367 @default.
• W2171010297 cites W2019929742 @default.
• W2171010297 cites W2020313062 @default.
• W2171010297 cites W2020830322 @default.
• W2171010297 cites W2020831296 @default.
• W2171010297 cites W2023401600 @default.
• W2171010297 cites W2026117336 @default.
• W2171010297 cites W2027488634 @default.
• W2171010297 cites W2029286778 @default.
• W2171010297 cites W2030517991 @default.
• W2171010297 cites W2034991912 @default.
• W2171010297 cites W2035381229 @default.
• W2171010297 cites W2037279051 @default.
• W2171010297 cites W2038238762 @default.
• W2171010297 cites W2039525616 @default.
• W2171010297 cites W2040406581 @default.
• W2171010297 cites W2041784704 @default.
• W2171010297 cites W2044696697 @default.
• W2171010297 cites W2047100770 @default.
• W2171010297 cites W2048610728 @default.
• W2171010297 cites W2049782851 @default.
• W2171010297 cites W2051035168 @default.
• W2171010297 cites W2051954664 @default.
• W2171010297 cites W2052924278 @default.
• W2171010297 cites W2056058417 @default.
• W2171010297 cites W2063012247 @default.
• W2171010297 cites W2064024045 @default.
• W2171010297 cites W2067877984 @default.
• W2171010297 cites W2069384815 @default.
• W2171010297 cites W2072731239 @default.
• W2171010297 cites W2079409197 @default.
• W2171010297 cites W2080406700 @default.
• W2171010297 cites W2081093364 @default.
• W2171010297 cites W2082124830 @default.
• W2171010297 cites W2082770850 @default.
• W2171010297 cites W2083228186 @default.
• W2171010297 cites W2083915110 @default.
• W2171010297 cites W2085288893 @default.
• W2171010297 cites W2087669579 @default.
• W2171010297 cites W2090227862 @default.

• next