FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2171079551> ?p ?o ?g. }

• W2171079551 endingPage "71" @default.
• W2171079551 startingPage "47" @default.
• W2171079551 abstract "1,8-Cineole is a widely distributed odorant that also shows physiological effects, but whose human metabolism has hitherto not been extensively investigated. The aim of the present study was, thus, to characterise the metabolites of 1,8-cineole, identified previously in human milk, after the oral intake of 100 mg of this substance. Special emphasis was placed on the enantiomeric composition of the metabolites since these data may provide important insights into potential biotransformation pathways, as well as potential biological activities of these substances, for example on the breastfed child. The volatile fraction of the human milk samples was therefore isolated via Solvent Assisted Flavour Evaporation (SAFE) and subjected to gas chromatography-mass spectrometry (GC-MS). The absolute concentrations of each metabolite were determined by matrix calibration with an internal standard, and the ratios of enantiomers were analysed on chiral capillaries. The concentrations varied over a broad range, from traces in the upper ng/kg region up to 40 µg/kg milk, with the exception of the main metabolite α2-hydroxy-1,8-cineole that showed concentrations of 100-250 µg/kg. Also, large inter- and intra-individual variations were recorded for the enantiomers, with nearly enantiomerically pure α2-hydroxy- and 3-oxo-1,8-cineole, while all other metabolites showed ratios of ~30:70 to 80:20." @default.
• W2171079551 created "2016-06-24" @default.
• W2171079551 creator A5017328382 @default.
• W2171079551 creator A5075182888 @default.
• W2171079551 date "2013-01-30" @default.
• W2171079551 modified "2023-09-26" @default.
• W2171079551 title "Characterisation of the Metabolites of 1,8-Cineole Transferred into Human Milk: Concentrations and Ratio of Enantiomers" @default.
• W2171079551 cites W112385937 @default.
• W2171079551 cites W1971222995 @default.
• W2171079551 cites W1979426677 @default.
• W2171079551 cites W1981919767 @default.
• W2171079551 cites W1982955445 @default.
• W2171079551 cites W1984061511 @default.
• W2171079551 cites W1985566453 @default.
• W2171079551 cites W1991004420 @default.
• W2171079551 cites W1994334380 @default.
• W2171079551 cites W1995647565 @default.
• W2171079551 cites W2012285092 @default.
• W2171079551 cites W2013057809 @default.
• W2171079551 cites W2020249064 @default.
• W2171079551 cites W2020587103 @default.
• W2171079551 cites W2031933043 @default.
• W2171079551 cites W2049848613 @default.
• W2171079551 cites W2050938512 @default.
• W2171079551 cites W2054579579 @default.
• W2171079551 cites W2054595289 @default.
• W2171079551 cites W2055677010 @default.
• W2171079551 cites W2060554485 @default.
• W2171079551 cites W2066430720 @default.
• W2171079551 cites W2068644259 @default.
• W2171079551 cites W2069913046 @default.
• W2171079551 cites W2075748739 @default.
• W2171079551 cites W2076019452 @default.
• W2171079551 cites W2077075563 @default.
• W2171079551 cites W2081730299 @default.
• W2171079551 cites W2082478751 @default.
• W2171079551 cites W2084826641 @default.
• W2171079551 cites W2085456920 @default.
• W2171079551 cites W2106195907 @default.
• W2171079551 cites W2109978434 @default.
• W2171079551 cites W2123139119 @default.
• W2171079551 cites W2126332858 @default.
• W2171079551 cites W2134772029 @default.
• W2171079551 cites W2144058395 @default.
• W2171079551 cites W2149236211 @default.
• W2171079551 cites W2150429652 @default.
• W2171079551 cites W2166026984 @default.
• W2171079551 cites W2748569300 @default.
• W2171079551 cites W2952997412 @default.
• W2171079551 cites W4211019970 @default.
• W2171079551 cites W4212939994 @default.
• W2171079551 cites W4236464777 @default.
• W2171079551 doi "https://doi.org/10.3390/metabo3010047" @default.
• W2171079551 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3901259" @default.
• W2171079551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24957890" @default.
• W2171079551 hasPublicationYear "2013" @default.
• W2171079551 type Work @default.
• W2171079551 sameAs 2171079551 @default.
• W2171079551 citedByCount "31" @default.
• W2171079551 countsByYear W21710795512013 @default.
• W2171079551 countsByYear W21710795512014 @default.
• W2171079551 countsByYear W21710795512015 @default.
• W2171079551 countsByYear W21710795512016 @default.
• W2171079551 countsByYear W21710795512017 @default.
• W2171079551 countsByYear W21710795512018 @default.
• W2171079551 countsByYear W21710795512019 @default.
• W2171079551 countsByYear W21710795512020 @default.
• W2171079551 countsByYear W21710795512021 @default.
• W2171079551 countsByYear W21710795512022 @default.
• W2171079551 countsByYear W21710795512023 @default.
• W2171079551 crossrefType "journal-article" @default.
• W2171079551 hasAuthorship W2171079551A5017328382 @default.
• W2171079551 hasAuthorship W2171079551A5075182888 @default.
• W2171079551 hasBestOaLocation W21710795511 @default.
• W2171079551 hasConcept C162356407 @default.
• W2171079551 hasConcept C181199279 @default.
• W2171079551 hasConcept C185592680 @default.
• W2171079551 hasConcept C205345274 @default.
• W2171079551 hasConcept C2777477808 @default.
• W2171079551 hasConcept C27881333 @default.
• W2171079551 hasConcept C43617362 @default.
• W2171079551 hasConcept C486523 @default.
• W2171079551 hasConcept C55493867 @default.
• W2171079551 hasConcept C71240020 @default.
• W2171079551 hasConceptScore W2171079551C162356407 @default.
• W2171079551 hasConceptScore W2171079551C181199279 @default.
• W2171079551 hasConceptScore W2171079551C185592680 @default.
• W2171079551 hasConceptScore W2171079551C205345274 @default.
• W2171079551 hasConceptScore W2171079551C2777477808 @default.
• W2171079551 hasConceptScore W2171079551C27881333 @default.
• W2171079551 hasConceptScore W2171079551C43617362 @default.
• W2171079551 hasConceptScore W2171079551C486523 @default.
• W2171079551 hasConceptScore W2171079551C55493867 @default.
• W2171079551 hasConceptScore W2171079551C71240020 @default.
• W2171079551 hasIssue "1" @default.
• W2171079551 hasLocation W21710795511 @default.
• W2171079551 hasLocation W21710795512 @default.
• W2171079551 hasLocation W21710795513 @default.

• next