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- W2171113587 startingPage "7095" @default.
- W2171113587 abstract "Synaptic nuclei of innervated muscle transcribe acetylcholine receptor (AChR) genes at a much higher level than extrasynaptic nuclei. To isolate candidate synaptic regulatory molecules responsible for the unique transcriptional potential of synaptic nuclei, we have taken a subtractive hybridization approach. Here, we report the cloning and characterization of a novel synapse-associated RNA, 7H4. 7H4 is expressed selectively in the endplate zone of skeletal muscle and is upregulated during early postnatal development and after denervation. Interestingly, the 7H4 gene has no introns, and yet two different-size RNAs with identical polyadenylated 3' ends are generated. Most intriguingly, the nucleotide sequence does not contain any significant open reading frames, suggesting that 7H4 may function as a noncoding RNA." @default.
- W2171113587 created "2016-06-24" @default.
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- W2171113587 creator A5031415255 @default.
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- W2171113587 date "1994-11-01" @default.
- W2171113587 modified "2023-09-23" @default.
- W2171113587 title "A novel synapse-associated noncoding RNA." @default.
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- W2171113587 doi "https://doi.org/10.1128/mcb.14.11.7095" @default.
- W2171113587 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/359243" @default.
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- W2171113587 hasPublicationYear "1994" @default.
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