Matches in SemOpenAlex for { <https://semopenalex.org/work/W2171127498> ?p ?o ?g. }
- W2171127498 endingPage "1684" @default.
- W2171127498 startingPage "1677" @default.
- W2171127498 abstract "Immunological treatment of malignant diseases in humans aiming at the induction and proliferation of antigen-specific T cells has made rapid progress in recent years. A growing number of tumour-associated antigens, potentially synergistic combinations with adjuvants, and various routes of application provide new opportunities for cancer vaccination. Therefore, a highly accurate assessment of vaccine-induced T cell responses is required. Three T cell assays (tetramers, intracellular cytokine flow cytometry and ELISPOT assay) have emerged as first-line methods for monitoring T cell induction during vaccination. These assays are relatively easy to perform, reliable, sensitive and allow an ex vivo T cell analysis at the single cell level. Although at this stage assays are not a defined surrogate marker for clinical efficacy, they already provide information concerning the immunological potency of a given vaccine. In particular, comparing immune responses under various treatment conditions will help to develop more clinically efficient tumour vaccination. Novel assays, such as CD107 staining, human leukocyte antigen/green fluorescent protein–antigen-presenting cells or microarrays, and assays determining functions, such as proliferation assays, are beginning to complement first-line monitoring assays." @default.
- W2171127498 created "2016-06-24" @default.
- W2171127498 creator A5066640097 @default.
- W2171127498 creator A5072568698 @default.
- W2171127498 creator A5073667628 @default.
- W2171127498 creator A5089758540 @default.
- W2171127498 date "2004-10-01" @default.
- W2171127498 modified "2023-09-25" @default.
- W2171127498 title "Immunological monitoring of cancer vaccine therapy" @default.
- W2171127498 cites W1483828791 @default.
- W2171127498 cites W1513089605 @default.
- W2171127498 cites W1521600055 @default.
- W2171127498 cites W1572267688 @default.
- W2171127498 cites W1577612079 @default.
- W2171127498 cites W1967684158 @default.
- W2171127498 cites W1970156673 @default.
- W2171127498 cites W1981480494 @default.
- W2171127498 cites W1988360904 @default.
- W2171127498 cites W1994340919 @default.
- W2171127498 cites W1995170364 @default.
- W2171127498 cites W2003983102 @default.
- W2171127498 cites W2006987944 @default.
- W2171127498 cites W2012148175 @default.
- W2171127498 cites W2019161272 @default.
- W2171127498 cites W2027125327 @default.
- W2171127498 cites W2030226186 @default.
- W2171127498 cites W2036961863 @default.
- W2171127498 cites W2040635819 @default.
- W2171127498 cites W2042468175 @default.
- W2171127498 cites W2046972425 @default.
- W2171127498 cites W2050227969 @default.
- W2171127498 cites W2051648607 @default.
- W2171127498 cites W2053311823 @default.
- W2171127498 cites W2054109196 @default.
- W2171127498 cites W2054678965 @default.
- W2171127498 cites W2074550162 @default.
- W2171127498 cites W2076730875 @default.
- W2171127498 cites W2077521424 @default.
- W2171127498 cites W2098005434 @default.
- W2171127498 cites W2107657398 @default.
- W2171127498 cites W2121976570 @default.
- W2171127498 cites W2127468351 @default.
- W2171127498 cites W2134453830 @default.
- W2171127498 cites W2137681991 @default.
- W2171127498 cites W2269774696 @default.
- W2171127498 doi "https://doi.org/10.1517/14712598.4.10.1677" @default.
- W2171127498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15461579" @default.
- W2171127498 hasPublicationYear "2004" @default.
- W2171127498 type Work @default.
- W2171127498 sameAs 2171127498 @default.
- W2171127498 citedByCount "30" @default.
- W2171127498 countsByYear W21711274982012 @default.
- W2171127498 countsByYear W21711274982013 @default.
- W2171127498 countsByYear W21711274982014 @default.
- W2171127498 countsByYear W21711274982016 @default.
- W2171127498 countsByYear W21711274982023 @default.
- W2171127498 crossrefType "journal-article" @default.
- W2171127498 hasAuthorship W2171127498A5066640097 @default.
- W2171127498 hasAuthorship W2171127498A5072568698 @default.
- W2171127498 hasAuthorship W2171127498A5073667628 @default.
- W2171127498 hasAuthorship W2171127498A5089758540 @default.
- W2171127498 hasConcept C147483822 @default.
- W2171127498 hasConcept C150903083 @default.
- W2171127498 hasConcept C203014093 @default.
- W2171127498 hasConcept C207001950 @default.
- W2171127498 hasConcept C22070199 @default.
- W2171127498 hasConcept C26291073 @default.
- W2171127498 hasConcept C2776090121 @default.
- W2171127498 hasConcept C2777701055 @default.
- W2171127498 hasConcept C2779053233 @default.
- W2171127498 hasConcept C502942594 @default.
- W2171127498 hasConcept C553184892 @default.
- W2171127498 hasConcept C71924100 @default.
- W2171127498 hasConcept C86803240 @default.
- W2171127498 hasConcept C8891405 @default.
- W2171127498 hasConceptScore W2171127498C147483822 @default.
- W2171127498 hasConceptScore W2171127498C150903083 @default.
- W2171127498 hasConceptScore W2171127498C203014093 @default.
- W2171127498 hasConceptScore W2171127498C207001950 @default.
- W2171127498 hasConceptScore W2171127498C22070199 @default.
- W2171127498 hasConceptScore W2171127498C26291073 @default.
- W2171127498 hasConceptScore W2171127498C2776090121 @default.
- W2171127498 hasConceptScore W2171127498C2777701055 @default.
- W2171127498 hasConceptScore W2171127498C2779053233 @default.
- W2171127498 hasConceptScore W2171127498C502942594 @default.
- W2171127498 hasConceptScore W2171127498C553184892 @default.
- W2171127498 hasConceptScore W2171127498C71924100 @default.
- W2171127498 hasConceptScore W2171127498C86803240 @default.
- W2171127498 hasConceptScore W2171127498C8891405 @default.
- W2171127498 hasIssue "10" @default.
- W2171127498 hasLocation W21711274981 @default.
- W2171127498 hasLocation W21711274982 @default.
- W2171127498 hasOpenAccess W2171127498 @default.
- W2171127498 hasPrimaryLocation W21711274981 @default.
- W2171127498 hasRelatedWork W1996150995 @default.
- W2171127498 hasRelatedWork W1999536736 @default.
- W2171127498 hasRelatedWork W2059844374 @default.
- W2171127498 hasRelatedWork W2084199936 @default.