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- W2171145900 abstract "Children with malignancies admitted to pediatric intensive care units (PICUs) for complications of their treatment regimes have a high mortality. There are seven previous publications addressing the outcome of this group of patients. We retrospectively analyzed data from 171 admissions (134 patients) to the PICU for predictors of outcome. The most frequent underlying diagnosis was acute lymphoblastic leukemia (ALL) (n = 23, 17%) followed by post-bone marrow transplant (DMT) (n = 12, 9%), but a wide variety of tumors were represented. Sixty-three children were admitted with suspected sepsis, 58 with positive cultures. This represents the largest series published. Mortality for sepsis was 53% and for systemic inflammatory response syndrome (SIRS) (negative cultures), 80%. Logistic regression analysis revealed the number of organs failed, day 1 PRISM score, and the dose and type of inotropes required to be independent predictors of mortality. The need for ventilation alone was not an independent predictor of..." @default.
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- W2171145900 date "2001-01-10" @default.
- W2171145900 modified "2023-09-26" @default.
- W2171145900 title "Outcome and Predictors of Mortality in Pediatric Oncology Patients Requiring Intensive Care" @default.
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- W2171145900 doi "https://doi.org/10.1046/j.1525-1489.2001.00029.x" @default.
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