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• W2171167071 startingPage "1003" @default.
• W2171167071 abstract "An in vitro transposition system, developed to facilitate gene disruption in Deinococcus radiodurans R1, has been used to inactivate the gene designated dr1819 in uvrA-1(+) and uvrA-1 backgrounds. dr1819 encodes a protein with homology to a UV DNA damage endonuclease expressed by Schizosaccharomyces pombe. Interruption of dr1819 greatly sensitizes the uvrA-1 strain but not the uvrA-1(+) strain to UV light, indicating that the dr1819 gene product is a component in a DNA repair pathway that can compensate for the loss of nucleotide excision repair in this species. Clones of dr1819 will restore UV resistance to UVS78, a uvrA-1 uvsE strain, indicating that dr1819 and uvsE are the same locus." @default.
• W2171167071 created "2016-06-24" @default.
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• W2171167071 date "2002-02-15" @default.
• W2171167071 modified "2023-10-02" @default.
• W2171167071 title "Genetic Evidence that the <i>uvsE</i> Gene Product of <i>Deinococcus radiodurans</i> R1 Is a UV Damage Endonuclease" @default.
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• W2171167071 doi "https://doi.org/10.1128/jb.184.4.1003-1009.2002" @default.
• W2171167071 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/134819" @default.
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