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• W2171186319 abstract "Purpose: Transglutaminase 2 (TGase 2) is expressed by tumor necrosis factor-<TEX>${alpha}$</TEX> in various carcinoma. The role of TGase 2 expression in salivary gland tumors is not clear yet. Established slaivary gland tumor (SGT)cell line has been used to study the pathogenesis of salivary gland adenocarcinoma on a cellular level in vitro. The pupose of this study were to examine mRNA expression of TGase 2 in SGT cell line compared to other tumor cell lines, and to apply these results to the pathogenesis of salivary gland tumor. Materials and Methods: After SGT, SCC-15, HN 4, and HeLa tumor cell lines were cultured under preconfl uency, and 3 days after postconfl uency, the cells were harvested for total RNA extraction and cDNA preparation. Result: Reverse transcription polymerase chain reaction for semiquantitative mRNA analysis was done. TGase 2 mRNA expression was not induced by confl uency in all the cell lines. TGase 2 mRNA expression was variable but markedly enhanced in SGT cell line. Conclusion: mRNA expression of TGase 2 should play an important role in the pathogenesis of SGT cell line originated from ductal cell." @default.
• W2171186319 created "2016-06-24" @default.
• W2171186319 creator A5059820833 @default.
• W2171186319 creator A5069955409 @default.
• W2171186319 date "2013-06-30" @default.
• W2171186319 modified "2023-09-26" @default.
• W2171186319 title "Transglutaminase 2 mRNA Expression in Salivary Gland Tumor Cell Line" @default.
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• W2171186319 doi "https://doi.org/10.5856/jkds.2013.6.1.22" @default.
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