Matches in SemOpenAlex for { <https://semopenalex.org/work/W2171241390> ?p ?o ?g. }
- W2171241390 endingPage "4067" @default.
- W2171241390 startingPage "4060" @default.
- W2171241390 abstract "Single crystals of a lipophilic G-quadruplex formed by 5‘-tert-butyl-dimethylsilyl-2‘,3‘,-di-O-isopropylidene G 2 were obtained from a CH3CN solution containing potassium picrate and cesium picrate. The X-ray structure showed that 16 units of G 2 and 4 equiv of alkali picrate form the lipophilic G-quadruplex. The quadruplex has a filled cation channel, with three K+ ions and one Cs+ ion located along its central axis. The quadruplex is formed by a pair of head-to-tail (G 2)8-K+ octamers. Both octamers use eight carbonyl oxygens to coordinate K+. The two (G 2)8-K+ octamers are of opposite polarity, being coaxially stacked in a head-to-head orientation. A Cs+ cation, with an unusual coordination geometry, caps the cation channel. The Cs+ is coordinated to four acetonitrile solvent molecules in an η2-fashion. Within an octamer the two tetramers are stacked so that they are 3.3 Å apart and twisted by 30°. A second stacking interaction is defined by the head-to-head arrangement between the two (G 2)8-K+ octamers. This stacking, with a 90° twist, positions the exocyclic amines of the central two quartets so that both exocyclic NH2B protons can hydrogen bond to the picrate anions that rim the quadruplex equator. The four picrates form an anionic belt that wraps around the cation channel. The sugars are well ordered in the structure. Circular dichroism spectra indicate that the G-quadruplex retains its helical structure in chlorinated solvents." @default.
- W2171241390 created "2016-06-24" @default.
- W2171241390 creator A5038253028 @default.
- W2171241390 creator A5060748268 @default.
- W2171241390 creator A5071829259 @default.
- W2171241390 creator A5082845641 @default.
- W2171241390 creator A5088000045 @default.
- W2171241390 date "2000-04-13" @default.
- W2171241390 modified "2023-10-16" @default.
- W2171241390 title "Toward Artificial Ion Channels: A Lipophilic G-Quadruplex" @default.
- W2171241390 cites W1963673259 @default.
- W2171241390 cites W1968006721 @default.
- W2171241390 cites W1986648841 @default.
- W2171241390 cites W1992411122 @default.
- W2171241390 cites W1993091782 @default.
- W2171241390 cites W1993190737 @default.
- W2171241390 cites W1994214442 @default.
- W2171241390 cites W1998521854 @default.
- W2171241390 cites W2000122226 @default.
- W2171241390 cites W2003521255 @default.
- W2171241390 cites W2007373812 @default.
- W2171241390 cites W2009623055 @default.
- W2171241390 cites W2011844193 @default.
- W2171241390 cites W2018632557 @default.
- W2171241390 cites W2018635753 @default.
- W2171241390 cites W2024021494 @default.
- W2171241390 cites W2027925443 @default.
- W2171241390 cites W2041550387 @default.
- W2171241390 cites W2042450595 @default.
- W2171241390 cites W2043138915 @default.
- W2171241390 cites W2046320299 @default.
- W2171241390 cites W2048172946 @default.
- W2171241390 cites W2052968074 @default.
- W2171241390 cites W2055661937 @default.
- W2171241390 cites W2057953526 @default.
- W2171241390 cites W2063567177 @default.
- W2171241390 cites W2065023009 @default.
- W2171241390 cites W2067614221 @default.
- W2171241390 cites W2074677328 @default.
- W2171241390 cites W2076102655 @default.
- W2171241390 cites W2078588680 @default.
- W2171241390 cites W2079630507 @default.
- W2171241390 cites W2081850653 @default.
- W2171241390 cites W2088409695 @default.
- W2171241390 cites W2090115145 @default.
- W2171241390 cites W2090603223 @default.
- W2171241390 cites W2091876286 @default.
- W2171241390 cites W2092377322 @default.
- W2171241390 cites W2095772405 @default.
- W2171241390 cites W2107878103 @default.
- W2171241390 cites W2128179591 @default.
- W2171241390 cites W2148066840 @default.
- W2171241390 cites W2167590372 @default.
- W2171241390 cites W2315823934 @default.
- W2171241390 cites W280694366 @default.
- W2171241390 cites W2949707128 @default.
- W2171241390 doi "https://doi.org/10.1021/ja9925148" @default.
- W2171241390 hasPublicationYear "2000" @default.
- W2171241390 type Work @default.
- W2171241390 sameAs 2171241390 @default.
- W2171241390 citedByCount "215" @default.
- W2171241390 countsByYear W21712413902012 @default.
- W2171241390 countsByYear W21712413902013 @default.
- W2171241390 countsByYear W21712413902014 @default.
- W2171241390 countsByYear W21712413902015 @default.
- W2171241390 countsByYear W21712413902016 @default.
- W2171241390 countsByYear W21712413902017 @default.
- W2171241390 countsByYear W21712413902018 @default.
- W2171241390 countsByYear W21712413902019 @default.
- W2171241390 countsByYear W21712413902020 @default.
- W2171241390 countsByYear W21712413902021 @default.
- W2171241390 countsByYear W21712413902022 @default.
- W2171241390 countsByYear W21712413902023 @default.
- W2171241390 crossrefType "journal-article" @default.
- W2171241390 hasAuthorship W2171241390A5038253028 @default.
- W2171241390 hasAuthorship W2171241390A5060748268 @default.
- W2171241390 hasAuthorship W2171241390A5071829259 @default.
- W2171241390 hasAuthorship W2171241390A5082845641 @default.
- W2171241390 hasAuthorship W2171241390A5088000045 @default.
- W2171241390 hasConcept C104317684 @default.
- W2171241390 hasConcept C112887158 @default.
- W2171241390 hasConcept C133571119 @default.
- W2171241390 hasConcept C145148216 @default.
- W2171241390 hasConcept C173681060 @default.
- W2171241390 hasConcept C178790620 @default.
- W2171241390 hasConcept C185592680 @default.
- W2171241390 hasConcept C2776421670 @default.
- W2171241390 hasConcept C32909587 @default.
- W2171241390 hasConcept C33347731 @default.
- W2171241390 hasConcept C55493867 @default.
- W2171241390 hasConcept C64927066 @default.
- W2171241390 hasConcept C71240020 @default.
- W2171241390 hasConcept C8010536 @default.
- W2171241390 hasConcept C84772758 @default.
- W2171241390 hasConceptScore W2171241390C104317684 @default.
- W2171241390 hasConceptScore W2171241390C112887158 @default.
- W2171241390 hasConceptScore W2171241390C133571119 @default.
- W2171241390 hasConceptScore W2171241390C145148216 @default.