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• W2171270671 abstract "The in vivo efficacy of LY333328, a new glycopeptide antibiotic, was compared with that of vancomycin by using the rabbit model of left-sided methicillin-resistant Staphylococcus aureus endocarditis. Animals received LY333328 or vancomycin (25 mg/kg of body weight every 24 or 8 h, respectively) for 4 days. These drugs were equally effective in clearing bacteremia and in reducing bacterial counts in vegetations and tissues. We conclude that in this model, LY333328 was microbiologically effective and may be a therapeutic alternative to vancomycin." @default.
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• W2171270671 date "1998-04-01" @default.
• W2171270671 modified "2023-10-16" @default.
• W2171270671 title "Efficacy of LY333328 against Experimental Methicillin-Resistant <i>Staphylococcus aureus</i> Endocarditis" @default.
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• W2171270671 doi "https://doi.org/10.1128/aac.42.4.981" @default.
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