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• W2171439482 abstract "We have read with great interest the article by Puttonen et al. about the association between shift work and subclinical atherosclerosis in young people [ [1] Puttonen S, Kivimaki M, Elovainio M, et al. Shift work in young adults and carotid artery intima-media thickness: The Cardiovascular Risk in Young Finns study. Atherosclerosis 2009; epub. Google Scholar ]. The authors reported that shift workers showed a higher carotid intima-media thickness (IMT) and a 2.2-fold increased risk of carotid plaques than those observed in day workers. Unfortunately, shift work schedule has been associated with several deleterious effects on the cardiovascular and metabolic systems. For instance, shift work was associated with a significant high risk of death due to ischemic heart disease [ 2 Fujino Y. Iso H. Tamakoshi A. et al. A prospective cohort study of shift work and risk of ischemic heart disease in Japanese male workers. Am J Epidemiol. 2006; 164: 128-135 Crossref PubMed Scopus (143) Google Scholar , 3 Knutsson A. Akerstedt T. Jonsson B.G. Orth-Gomer K. Increased risk of ischaemic heart disease in shift workers. Lancet. 1986; 2: 89-92 Abstract PubMed Scopus (378) Google Scholar ]. In fact, results from large prospective studies showed that shift work is associated with myocardial infarction [ [4] Knutsson A. Hallquist J. Reuterwall C. Theorell T. Akerstedt T. Shiftwork and myocardial infarction: a case-control study. Occup Environ Med. 1999; 56: 46-50 Crossref PubMed Scopus (160) Google Scholar ]. A recently published study showed that shift work is a risk factor for myocardial infarction even at younger ages [ [5] Haupt C.M. Alte D. Dorr M. et al. The relation of exposure to shift work with atherosclerosis and myocardial infarction in a general population. Atherosclerosis. 2008; PubMed Google Scholar ]. Otherwise, we observed that shift workers exhibit most of the risk factors of the cardiometabolic syndrome, including elevated body mass index, waist–hip ratio, diastolic blood pressure, fasting insulin, HOMA index and triglycerides [ [6] Sookoian S. Gemma C. Fernandez G.T. et al. Effects of rotating shift work on biomarkers of metabolic syndrome and inflammation. J Intern Med. 2007; 261: 285-292 Crossref PubMed Scopus (213) Google Scholar ]. In addition, our results emphasize the presence of low-grade inflammation in shift workers, which may be a contributing factor to the health problems that characterize the shift work. Taken together, all these data are of remarkable importance as shift work contributes to the morbimortality of cardiovascular diseases in young exposed people as emphasized by Puttonen et al. [ [1] Puttonen S, Kivimaki M, Elovainio M, et al. Shift work in young adults and carotid artery intima-media thickness: The Cardiovascular Risk in Young Finns study. Atherosclerosis 2009; epub. Google Scholar ]. It must also be noted that shift workers represent approximately 20% of the workforce worldwide." @default.
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• W2171439482 date "2009-12-01" @default.
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• W2171439482 title "Shift work and subclinical atherosclerosis: Recommendations for fatty liver disease detection" @default.
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• W2171439482 doi "https://doi.org/10.1016/j.atherosclerosis.2009.06.008" @default.
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