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• W2171444483 abstract "High consequence human pathogenic viruses must be handled at biosafety level 2, 3 or 4 and must be rendered non-infectious before they can be utilized for molecular or immunological applications at lower biosafety levels. Here we evaluate psoralen-inactivated Arena-, Bunya-, Corona-, Filo-, Flavi- and Orthomyxoviruses for their suitability as antigen in immunological processes and as template for reverse transcription PCR and sequencing. The method of virus inactivation using a psoralen molecule appears to have broad applicability to RNA viruses and to leave both the particle and RNA of the treated virus intact, while rendering the virus non-infectious." @default.
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• W2171444483 date "2015-11-12" @default.
• W2171444483 modified "2023-10-16" @default.
• W2171444483 title "Psoralen Inactivation of Viruses: A Process for the Safe Manipulation of Viral Antigen and Nucleic Acid" @default.
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• W2171444483 doi "https://doi.org/10.3390/v7112912" @default.
• W2171444483 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4664985" @default.
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