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- W2171456688 abstract "The randomized controlled trial (RCT) is one of the simplest but most powerful tools of research. It is the most rigorous way of determining whether a cause–effect relationship exists between treatment and outcome and for assessing the cost-effectiveness of a treatment. Through the randomization bias will be avoided by distributing the characteristics of patients that may influence outcome randomly between treatment groups so that any difference in outcome can be explained only by treatment. These characteristics might be demographic in nature in the form of age or prognostic factors such as clinical history or disease severity. For instance, menopausal status may influence outcome of treatment for breast cancer. This article is aimed at reviewing the general principles, importance of the RCT and the reason for its use in clinical research." @default.
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- W2171456688 date "2009-04-01" @default.
- W2171456688 modified "2023-10-18" @default.
- W2171456688 title "Randomized controlled trial: the most powerful tool in clinical research" @default.
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- W2171456688 doi "https://doi.org/10.12968/ajmw.2009.3.2.41859" @default.
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