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- W2171502904 abstract "Abstract It was considered that the first dose reaction occurring with prazosin may have been due either to hypotension or to a specific reduction in cerebral blood flow. The development of a quantitative non-invasion nuclear medicine technique for cerebral flow has now made it possible to investigate the effects of prazosin on cerebral blood flow in hypertensive patients. This double-blind study showed a significant decrease in BP and a small just significant increase in cerebral blood flow following a single 1-mg dose of prazosin, when compared with a placebo. From these results, it is unlikely that the first dose reactions which occurred with prazosin were due to a specific reduction in cerebral blood flow." @default.
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- W2171502904 date "1980-12-01" @default.
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- W2171502904 title "Measurement of the effects of a single dose of prazosin on the cerebral blood flow in hypertensive patients" @default.
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- W2171502904 doi "https://doi.org/10.1136/pgmj.56.662.818" @default.
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