Matches in SemOpenAlex for { <https://semopenalex.org/work/W2171681751> ?p ?o ?g. }
- W2171681751 endingPage "668" @default.
- W2171681751 startingPage "661" @default.
- W2171681751 abstract "Sperm-zona adhesion is an essential event in mammalian fertilization, failure of which causes sterility. However, the molecular mechanisms involved in this process are still poorly understood. It has been suggested by few laboratories studying gamete interaction that acrosomal molecules are implicated in sperm-zona pellucida adhesion prior to the acrosome reaction (AR). Zonadhesin, a sperm-specific protein located in the acrosome is critically involved in zona binding. Here we describe the cellular and molecular interaction of zonadhesin during fertilization and also discuss its role in species-specific gamete interaction--an intriguing question in biology. We propose a model in which sperm could transiently expose acrosomal molecules that adhere to the zona independently of the AR in a 'kiss and run' mechanism. This could be a valuable framework for further investigations and a detailed understanding of the molecular events during gamete adhesion is likely to provide new approaches for the design of more effective male contraceptives and better diagnostic methods for sperm dysfunction." @default.
- W2171681751 created "2016-06-24" @default.
- W2171681751 creator A5043106314 @default.
- W2171681751 creator A5013361905 @default.
- W2171681751 date "2011-05-20" @default.
- W2171681751 modified "2023-10-16" @default.
- W2171681751 title "Role of zonadhesin during sperm–egg interaction: a species-specific acrosomal molecule with multiple functions" @default.
- W2171681751 cites W1564650596 @default.
- W2171681751 cites W1603474692 @default.
- W2171681751 cites W1922120593 @default.
- W2171681751 cites W1966465076 @default.
- W2171681751 cites W1967730128 @default.
- W2171681751 cites W1968209548 @default.
- W2171681751 cites W1968843575 @default.
- W2171681751 cites W1972895952 @default.
- W2171681751 cites W1977229240 @default.
- W2171681751 cites W1985439366 @default.
- W2171681751 cites W1991064729 @default.
- W2171681751 cites W2001463676 @default.
- W2171681751 cites W2002053748 @default.
- W2171681751 cites W2002094277 @default.
- W2171681751 cites W2012501909 @default.
- W2171681751 cites W2015373368 @default.
- W2171681751 cites W2018217912 @default.
- W2171681751 cites W2022628365 @default.
- W2171681751 cites W2026057878 @default.
- W2171681751 cites W2028269459 @default.
- W2171681751 cites W2032802646 @default.
- W2171681751 cites W2040080912 @default.
- W2171681751 cites W2040240749 @default.
- W2171681751 cites W2041238814 @default.
- W2171681751 cites W2044216570 @default.
- W2171681751 cites W2044297412 @default.
- W2171681751 cites W2045580924 @default.
- W2171681751 cites W2051632261 @default.
- W2171681751 cites W2056037856 @default.
- W2171681751 cites W2061648581 @default.
- W2171681751 cites W2065790464 @default.
- W2171681751 cites W2071684520 @default.
- W2171681751 cites W2072155012 @default.
- W2171681751 cites W2072858937 @default.
- W2171681751 cites W2076068862 @default.
- W2171681751 cites W2076373755 @default.
- W2171681751 cites W2079802547 @default.
- W2171681751 cites W2089314043 @default.
- W2171681751 cites W2091157702 @default.
- W2171681751 cites W2093409717 @default.
- W2171681751 cites W2112282765 @default.
- W2171681751 cites W2115102751 @default.
- W2171681751 cites W2117958760 @default.
- W2171681751 cites W2118512011 @default.
- W2171681751 cites W2118556506 @default.
- W2171681751 cites W2119809913 @default.
- W2171681751 cites W2122473562 @default.
- W2171681751 cites W2124608202 @default.
- W2171681751 cites W2127489545 @default.
- W2171681751 cites W2127713704 @default.
- W2171681751 cites W2130220696 @default.
- W2171681751 cites W2134533697 @default.
- W2171681751 cites W2137639709 @default.
- W2171681751 cites W2145534942 @default.
- W2171681751 cites W2146850044 @default.
- W2171681751 cites W2147904388 @default.
- W2171681751 cites W2149817860 @default.
- W2171681751 cites W2150333796 @default.
- W2171681751 cites W2152727487 @default.
- W2171681751 cites W2154938203 @default.
- W2171681751 cites W2162585947 @default.
- W2171681751 cites W2167049138 @default.
- W2171681751 cites W2343477951 @default.
- W2171681751 doi "https://doi.org/10.1093/molehr/gar039" @default.
- W2171681751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21602212" @default.
- W2171681751 hasPublicationYear "2011" @default.
- W2171681751 type Work @default.
- W2171681751 sameAs 2171681751 @default.
- W2171681751 citedByCount "33" @default.
- W2171681751 countsByYear W21716817512012 @default.
- W2171681751 countsByYear W21716817512013 @default.
- W2171681751 countsByYear W21716817512014 @default.
- W2171681751 countsByYear W21716817512015 @default.
- W2171681751 countsByYear W21716817512016 @default.
- W2171681751 countsByYear W21716817512017 @default.
- W2171681751 countsByYear W21716817512018 @default.
- W2171681751 countsByYear W21716817512019 @default.
- W2171681751 countsByYear W21716817512020 @default.
- W2171681751 countsByYear W21716817512021 @default.
- W2171681751 countsByYear W21716817512022 @default.
- W2171681751 countsByYear W21716817512023 @default.
- W2171681751 crossrefType "journal-article" @default.
- W2171681751 hasAuthorship W2171681751A5013361905 @default.
- W2171681751 hasAuthorship W2171681751A5043106314 @default.
- W2171681751 hasBestOaLocation W21716817511 @default.
- W2171681751 hasConcept C16685009 @default.
- W2171681751 hasConcept C196843134 @default.
- W2171681751 hasConcept C2776010925 @default.
- W2171681751 hasConcept C2776690073 @default.
- W2171681751 hasConcept C2776803348 @default.
- W2171681751 hasConcept C2778252442 @default.