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- W2171741654 abstract "This thesis investigates the various components required for the development of a patient position verification system to replace the existing system used by the proton facilities of iThemba LABS1. The existing system is based on the visual comparison of a portal radiograph (PR) of the patient in the current treatment position and a digitally reconstructed radiograph (DRR) of the patient in the correct treatment position. This system is not only of limited accuracy, but labour intensive and time-consuming. Inaccuracies in patient position are detrimental to the effectiveness of proton therapy, and elongated treatment times add to patient trauma. A new system is needed that is accurate, fast, robust and automatic. Automatic verification is achieved by using image registration techniques to compare the PR and DRRs. The registration process finds a rigid body transformation which estimates the difference between the current position and the correct position by minimizing the measure which compares the two images. The image registration process therefore consists of four main components: the DRR, the PR, the measure for comparing the two images and the minimization method. The ray-tracing algorithm by Jacobs was implemented to generate the DRRs, with the option to use X-ray attenuation calibration curves and beam hardening correction curves to generate DRRs that approximate the PRs acquired with iThemba LABS’s digital portal radiographic system (DPRS) better. Investigations were performed mostly on simulated PRs generated from Laboratory for accelerator based sciences" @default.
- W2171741654 created "2016-06-24" @default.
- W2171741654 creator A5009051972 @default.
- W2171741654 date "2006-12-01" @default.
- W2171741654 modified "2023-09-26" @default.
- W2171741654 title "Verification of patient position for proton therapy using Portal X-Rays and Digitally Reconstructed Radiographs" @default.
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- W2171741654 hasPublicationYear "2006" @default.
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