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• W2171749284 abstract "In humans, there are large individual differences in the levels of vagal modulation of resting heart rate. High levels are a recognized index of cardiac health, whereas low levels are considered an important risk factor for cardiovascular morbidity and mortality. Several factors are thought to contribute significantly to this inter-individual variability. While regular physical exercise seems to induce an increase in resting vagal tone, chronic life stress and psychosocial factors such as negative moods and personality traits appear associated with vagal withdrawal. Preclinical research has been attempting to clarify such relationships and to provide insights into the neurobiological mechanisms underlying vagal tone impairment/enhancement. This paper focuses on rat studies that have explored the effects of stress, psychosocial factors and physical exercise on vagal modulation of resting heart rate. Results are discussed with regard to: (i) individual differences in resting vagal tone, cardiac stress reactivity and arrhythmia vulnerability; (ii) elucidation of the neurobiological determinants of resting vagal tone." @default.
• W2171749284 created "2016-06-24" @default.
• W2171749284 creator A5035649042 @default.
• W2171749284 creator A5057350705 @default.
• W2171749284 date "2014-03-24" @default.
• W2171749284 modified "2023-09-27" @default.
• W2171749284 title "Vagal modulation of resting heart rate in rats: the role of stress, psychosocial factors, and physical exercise" @default.
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• W2171749284 doi "https://doi.org/10.3389/fphys.2014.00118" @default.
• W2171749284 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3970013" @default.
• W2171749284 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24715877" @default.
• W2171749284 hasPublicationYear "2014" @default.
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