FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2171800616> ?p ?o ?g. }

• W2171800616 endingPage "160" @default.
• W2171800616 startingPage "152" @default.
• W2171800616 abstract "Low serum 25-hydroxyvitamin D [25(OH)D] concentrations have been associated with insulin resistance, the metabolic syndrome, and type 2 diabetes. Because many non-Western immigrants in the Netherlands are vitamin D deficient, obese, and at high risk of diabetes, vitamin D supplementation may contribute to prevent diabetes and insulin resistance. We examined the effect of vitamin D supplementation on insulin sensitivity and β cell function in overweight, vitamin D–deficient, non-Western immigrants at high risk of diabetes. The study was a 16-wk, randomized, placebo-controlled trial. A total of 130 non-Western immigrants with prediabetes (fasting glucose concentration >5.5 mmol/L or random glucose concentration from 7.8 to 11.1 mmol/L) and vitamin D deficiency (serum 25[OH]D concentration <50 nmol/L) were randomly assigned after stratification by sex to receive either cholecalciferol (1200 IU/d) or a placebo for 16 wk. All participants received 500 mg Ca/d as calcium carbonate. The primary outcome was the difference in the area under the curve of insulin and glucose after a 75-g oral-glucose-tolerance test after 4 mo of treatment. Secondary outcomes were insulin-sensitivity variables, β cell–function variables, and metabolic syndrome. Mean serum 25(OH)D concentrations increased significantly in the vitamin D compared with placebo groups. After 4 mo of therapy, the mean between-group difference was 38 nmol/L (95% CI: 32.1, 43.9 nmol/L; P < 0.001). There was no significant effect on insulin sensitivity and β cell function. In a post hoc analysis, when patients with diabetes at baseline were excluded, a significant increase in the insulinogenic index was observed in participants who obtained a 25(OH)D concentration ≥60 nmol/L (P = 0.040). Vitamin D supplementation in non-Western vitamin D–deficient immigrants with prediabetes did not improve insulin sensitivity or β cell function or change the incidence of metabolic syndrome. However, after the exclusion of diabetic subjects, an improvement in the insulinogenic index was observed in participants who obtained a 25(OH)D concentration ≥60 nmol/L. This trial was registered at trialregister.nl as NTR1827." @default.
• W2171800616 created "2016-06-24" @default.
• W2171800616 creator A5001814301 @default.
• W2171800616 creator A5015921379 @default.
• W2171800616 creator A5019926739 @default.
• W2171800616 creator A5028760009 @default.
• W2171800616 creator A5033654838 @default.
• W2171800616 creator A5039490718 @default.
• W2171800616 creator A5046656254 @default.
• W2171800616 creator A5058475886 @default.
• W2171800616 creator A5071149552 @default.
• W2171800616 date "2014-07-01" @default.
• W2171800616 modified "2023-09-27" @default.
• W2171800616 title "Effect of moderate-dose vitamin D supplementation on insulin sensitivity in vitamin D–deficient non-Western immigrants in the Netherlands: a randomized placebo-controlled trial" @default.
• W2171800616 cites W1849648692 @default.
• W2171800616 cites W1940094357 @default.
• W2171800616 cites W1981084145 @default.
• W2171800616 cites W1985297370 @default.
• W2171800616 cites W1987400763 @default.
• W2171800616 cites W1999331118 @default.
• W2171800616 cites W2026437158 @default.
• W2171800616 cites W2026819373 @default.
• W2171800616 cites W2040219214 @default.
• W2171800616 cites W2042925852 @default.
• W2171800616 cites W2057089785 @default.
• W2171800616 cites W2057301426 @default.
• W2171800616 cites W2081845767 @default.
• W2171800616 cites W2088832793 @default.
• W2171800616 cites W2096717361 @default.
• W2171800616 cites W2101344945 @default.
• W2171800616 cites W2103714496 @default.
• W2171800616 cites W2106033766 @default.
• W2171800616 cites W2127609720 @default.
• W2171800616 cites W2129327282 @default.
• W2171800616 cites W2129760052 @default.
• W2171800616 cites W2131264460 @default.
• W2171800616 cites W2131946475 @default.
• W2171800616 cites W2131996809 @default.
• W2171800616 cites W2132605013 @default.
• W2171800616 cites W2132806782 @default.
• W2171800616 cites W2133795831 @default.
• W2171800616 cites W2140504583 @default.
• W2171800616 cites W2145545350 @default.
• W2171800616 cites W2148787194 @default.
• W2171800616 cites W2149699257 @default.
• W2171800616 cites W2153059487 @default.
• W2171800616 cites W2158741047 @default.
• W2171800616 cites W2159761131 @default.
• W2171800616 cites W2160234571 @default.
• W2171800616 cites W2164418602 @default.
• W2171800616 cites W2164882053 @default.
• W2171800616 cites W2247812590 @default.
• W2171800616 doi "https://doi.org/10.3945/ajcn.113.069260" @default.
• W2171800616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24898240" @default.
• W2171800616 hasPublicationYear "2014" @default.
• W2171800616 type Work @default.
• W2171800616 sameAs 2171800616 @default.
• W2171800616 citedByCount "67" @default.
• W2171800616 countsByYear W21718006162014 @default.
• W2171800616 countsByYear W21718006162015 @default.
• W2171800616 countsByYear W21718006162016 @default.
• W2171800616 countsByYear W21718006162017 @default.
• W2171800616 countsByYear W21718006162018 @default.
• W2171800616 countsByYear W21718006162019 @default.
• W2171800616 countsByYear W21718006162020 @default.
• W2171800616 countsByYear W21718006162021 @default.
• W2171800616 countsByYear W21718006162022 @default.
• W2171800616 countsByYear W21718006162023 @default.
• W2171800616 crossrefType "journal-article" @default.
• W2171800616 hasAuthorship W2171800616A5001814301 @default.
• W2171800616 hasAuthorship W2171800616A5015921379 @default.
• W2171800616 hasAuthorship W2171800616A5019926739 @default.
• W2171800616 hasAuthorship W2171800616A5028760009 @default.
• W2171800616 hasAuthorship W2171800616A5033654838 @default.
• W2171800616 hasAuthorship W2171800616A5039490718 @default.
• W2171800616 hasAuthorship W2171800616A5046656254 @default.
• W2171800616 hasAuthorship W2171800616A5058475886 @default.
• W2171800616 hasAuthorship W2171800616A5071149552 @default.
• W2171800616 hasBestOaLocation W21718006161 @default.
• W2171800616 hasConcept C124490489 @default.
• W2171800616 hasConcept C126322002 @default.
• W2171800616 hasConcept C134018914 @default.
• W2171800616 hasConcept C142724271 @default.
• W2171800616 hasConcept C204787440 @default.
• W2171800616 hasConcept C27081682 @default.
• W2171800616 hasConcept C2776940978 @default.
• W2171800616 hasConcept C2777180221 @default.
• W2171800616 hasConcept C2777391703 @default.
• W2171800616 hasConcept C2779306644 @default.
• W2171800616 hasConcept C2779668308 @default.
• W2171800616 hasConcept C2779740938 @default.
• W2171800616 hasConcept C2780106736 @default.
• W2171800616 hasConcept C2780586474 @default.
• W2171800616 hasConcept C511355011 @default.
• W2171800616 hasConcept C555293320 @default.
• W2171800616 hasConcept C71924100 @default.
• W2171800616 hasConceptScore W2171800616C124490489 @default.
• W2171800616 hasConceptScore W2171800616C126322002 @default.

• next