FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2171802514> ?p ?o ?g. }

• W2171802514 endingPage "712" @default.
• W2171802514 startingPage "709" @default.
• W2171802514 abstract "Point mutation of the BRAF gene is a genetic event that occurs in a subset of lung adenocarcinoma cases. For example, BRAF V600E is a driver mutation that can be effectively targeted using selective BRAF and/or MEK inhibitors. The present study hypothesized that an increase in BRAF copy number may be correlated with certain clinicopathological features of lung adenocarcinoma in Japanese patients. The BRAF gene copy number was analyzed using quantitative polymerase chain reaction amplifications in 29 surgically treated lung adenocarcinoma cases without EGFR or Kras mutations from Nagoya City University Hospital (Nagoya, Japan). Seven BRAF‑mutant cases were included. Increased BRAF gene copy number was identified in three lung adenocarcinoma patients (10.3%), all of which exhibited the V600E mutation. Using fluorescence in situ hybridization with BRAF‑specific and chromosome 7 centromeric probes, increased copy number status was associated with gene amplification or gain of chromosome 7. Although increased BRAF copy number was correlated with BRAF V600E mutations, numerical changes in BRAF copy number were rare and mild in lung adenocarcinoma, resulting in no significant difference in pathological tumor status or tumor stage." @default.
• W2171802514 created "2016-06-24" @default.
• W2171802514 creator A5027643210 @default.
• W2171802514 creator A5031327561 @default.
• W2171802514 creator A5040259759 @default.
• W2171802514 creator A5054361684 @default.
• W2171802514 creator A5055251317 @default.
• W2171802514 creator A5061491770 @default.
• W2171802514 creator A5081181660 @default.
• W2171802514 date "2014-11-20" @default.
• W2171802514 modified "2023-09-30" @default.
• W2171802514 title "Increased BRAF copy number in lung adenocarcinoma" @default.
• W2171802514 cites W1773107256 @default.
• W2171802514 cites W1966428098 @default.
• W2171802514 cites W1966869381 @default.
• W2171802514 cites W1981626262 @default.
• W2171802514 cites W1996141540 @default.
• W2171802514 cites W2002026641 @default.
• W2171802514 cites W2006195227 @default.
• W2171802514 cites W2006345374 @default.
• W2171802514 cites W2046639717 @default.
• W2171802514 cites W2058131495 @default.
• W2171802514 cites W2087992293 @default.
• W2171802514 cites W2104224322 @default.
• W2171802514 cites W2106116393 @default.
• W2171802514 cites W2106494998 @default.
• W2171802514 cites W2111580893 @default.
• W2171802514 cites W2123611729 @default.
• W2171802514 cites W2124662474 @default.
• W2171802514 cites W2128542677 @default.
• W2171802514 cites W2134950311 @default.
• W2171802514 cites W2136474966 @default.
• W2171802514 cites W2142989887 @default.
• W2171802514 cites W2150342781 @default.
• W2171802514 cites W2156078931 @default.
• W2171802514 cites W2160304102 @default.
• W2171802514 cites W2163798887 @default.
• W2171802514 cites W2328526878 @default.
• W2171802514 cites W2573814393 @default.
• W2171802514 doi "https://doi.org/10.3892/ol.2014.2719" @default.
• W2171802514 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4301492" @default.
• W2171802514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25621040" @default.
• W2171802514 hasPublicationYear "2014" @default.
• W2171802514 type Work @default.
• W2171802514 sameAs 2171802514 @default.
• W2171802514 citedByCount "6" @default.
• W2171802514 countsByYear W21718025142015 @default.
• W2171802514 countsByYear W21718025142016 @default.
• W2171802514 countsByYear W21718025142017 @default.
• W2171802514 countsByYear W21718025142018 @default.
• W2171802514 crossrefType "journal-article" @default.
• W2171802514 hasAuthorship W2171802514A5027643210 @default.
• W2171802514 hasAuthorship W2171802514A5031327561 @default.
• W2171802514 hasAuthorship W2171802514A5040259759 @default.
• W2171802514 hasAuthorship W2171802514A5054361684 @default.
• W2171802514 hasAuthorship W2171802514A5055251317 @default.
• W2171802514 hasAuthorship W2171802514A5061491770 @default.
• W2171802514 hasAuthorship W2171802514A5081181660 @default.
• W2171802514 hasBestOaLocation W21718025141 @default.
• W2171802514 hasConcept C104317684 @default.
• W2171802514 hasConcept C120821319 @default.
• W2171802514 hasConcept C121608353 @default.
• W2171802514 hasConcept C126322002 @default.
• W2171802514 hasConcept C141231307 @default.
• W2171802514 hasConcept C150194340 @default.
• W2171802514 hasConcept C176944494 @default.
• W2171802514 hasConcept C2776470698 @default.
• W2171802514 hasConcept C2777542201 @default.
• W2171802514 hasConcept C2777714996 @default.
• W2171802514 hasConcept C2781018059 @default.
• W2171802514 hasConcept C2781182431 @default.
• W2171802514 hasConcept C2781187634 @default.
• W2171802514 hasConcept C29537977 @default.
• W2171802514 hasConcept C2994225774 @default.
• W2171802514 hasConcept C30481170 @default.
• W2171802514 hasConcept C501734568 @default.
• W2171802514 hasConcept C502942594 @default.
• W2171802514 hasConcept C54355233 @default.
• W2171802514 hasConcept C55548728 @default.
• W2171802514 hasConcept C71924100 @default.
• W2171802514 hasConcept C7602840 @default.
• W2171802514 hasConcept C86803240 @default.
• W2171802514 hasConceptScore W2171802514C104317684 @default.
• W2171802514 hasConceptScore W2171802514C120821319 @default.
• W2171802514 hasConceptScore W2171802514C121608353 @default.
• W2171802514 hasConceptScore W2171802514C126322002 @default.
• W2171802514 hasConceptScore W2171802514C141231307 @default.
• W2171802514 hasConceptScore W2171802514C150194340 @default.
• W2171802514 hasConceptScore W2171802514C176944494 @default.
• W2171802514 hasConceptScore W2171802514C2776470698 @default.
• W2171802514 hasConceptScore W2171802514C2777542201 @default.
• W2171802514 hasConceptScore W2171802514C2777714996 @default.
• W2171802514 hasConceptScore W2171802514C2781018059 @default.
• W2171802514 hasConceptScore W2171802514C2781182431 @default.
• W2171802514 hasConceptScore W2171802514C2781187634 @default.
• W2171802514 hasConceptScore W2171802514C29537977 @default.
• W2171802514 hasConceptScore W2171802514C2994225774 @default.
• W2171802514 hasConceptScore W2171802514C30481170 @default.

• next