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• W2171848801 abstract "The influence of caspofungin on polymorphonuclear leukocyte (PMN) phagocytosis and intracellular killing of Candida albicans was investigated. Caspofungin, at all of the concentrations tested (2, 3.2, and 8 microg/ml), significantly increased intracellular killing by PMNs through its direct action on both yeast cells and PMNs, indicating the potential ability of caspofungin to synergize with phagocytes for candidal killing. Caspofungin may therefore constitute an effective therapeutic option for the treatment of invasive fungal infections, including those refractory to conventional treatment with azole agents." @default.
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• W2171848801 date "2010-09-01" @default.
• W2171848801 modified "2023-09-29" @default.
• W2171848801 title "Synergy of Caspofungin with Human Polymorphonuclear Granulocytes for Killing <i>Candida albicans</i>" @default.
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• W2171848801 doi "https://doi.org/10.1128/aac.01780-09" @default.
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