FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2171879002> ?p ?o ?g. }

• W2171879002 endingPage "169" @default.
• W2171879002 startingPage "166" @default.
• W2171879002 abstract "With expansion of lung cancer screening by computed tomography (CT) and increased incidence of adenocarcinoma, we encountered more peripheral nodules to be identified. We evaluated detection rates of the melanoma antigen genes (MAGE) RT-nested PCR using a common MAGE A1-6 primer in bronchoscopic washing samples from patients with bronchoscopically invisible peripheral nodules, and compared with those of conventional cytology and percutaneous needle aspiration biopsy (PCNB).Forty-two patients with bronchoscopically invisible peripheral lung nodules were studied. Bronchoscopic washing specimens were collected by instilling 20ml of normal saline into a tumor bearing segment and retrieving samples. Samples were split and analyzed by MAGE RT-PCR and conventional cytology. A PCNB was performed in all but two patients. Twenty-eight lesions were diagnosed as lung cancers and 14 as benign lung diseases. We evaluated MAGE A1-6 RT-nested PCR, cytology, and PCNB results and analyzed them according to histologic cell types and tumor sizes.In bronchial washing samples, the detection rates of MAGE A1-6 RT-nested PCR (67.9%) were higher than that of conventional cytology (21.4%, p=.04) and similar to that of PCNB (73.1%, p=.45) in 28 cancer patients. In terms of histologic types, the detection rates of MAGE A1-6 RT-nested PCR, conventional cytology, and PCNB were 78.6%, 21.4% and 64.3% in adenocarcinoma, 70%, 20% and 77.8% in squamous cell carcinoma, respectively. The sensitivity of conventional cytology was significantly lower than that of MAGE RT-nested PCR or PCNB regardless of tumor histology p=.04, p=.025, respectively, in adenocarcinoma; p=.035, p=.04, respectively, in squamous cell carcinoma). In terms of tumor size, the corresponding detection rates were 73.3%, 6.7% and 73.3% for tumors smaller than 3cm (N=15), and 61.5%, 38.5% and 72.7% for tumors larger than 3cm (N=13).MAGE A1-6 RT-nested PCR showed higher detection rates in the bronchial washes of peripheral lung cancer patients than conventional cytology testing. This method is simple and robust, and it could be effectively utilized as a peripheral lung cancer detection tool in clinical laboratories." @default.
• W2171879002 created "2016-06-24" @default.
• W2171879002 creator A5013601337 @default.
• W2171879002 creator A5013927834 @default.
• W2171879002 creator A5021661618 @default.
• W2171879002 creator A5026788596 @default.
• W2171879002 creator A5038406743 @default.
• W2171879002 creator A5048166383 @default.
• W2171879002 creator A5054994372 @default.
• W2171879002 creator A5057664407 @default.
• W2171879002 creator A5069360564 @default.
• W2171879002 creator A5076249309 @default.
• W2171879002 date "2009-08-01" @default.
• W2171879002 modified "2023-10-16" @default.
• W2171879002 title "The detection of peripheral lung cancer by MAGE A1–6 RT-nested PCR in bronchial washing specimens" @default.
• W2171879002 cites W1966107877 @default.
• W2171879002 cites W1970000032 @default.
• W2171879002 cites W1996926182 @default.
• W2171879002 cites W2002532888 @default.
• W2171879002 cites W2006987944 @default.
• W2171879002 cites W2033135238 @default.
• W2171879002 cites W2038219027 @default.
• W2171879002 cites W2059297569 @default.
• W2171879002 cites W2073252143 @default.
• W2171879002 cites W2096555825 @default.
• W2171879002 cites W2107389149 @default.
• W2171879002 cites W2109581888 @default.
• W2171879002 cites W2116058268 @default.
• W2171879002 cites W2124429289 @default.
• W2171879002 cites W2126560850 @default.
• W2171879002 cites W2137483531 @default.
• W2171879002 cites W2161343890 @default.
• W2171879002 cites W2161935580 @default.
• W2171879002 cites W2164065953 @default.
• W2171879002 doi "https://doi.org/10.1016/j.lungcan.2008.11.001" @default.
• W2171879002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19168258" @default.
• W2171879002 hasPublicationYear "2009" @default.
• W2171879002 type Work @default.
• W2171879002 sameAs 2171879002 @default.
• W2171879002 citedByCount "10" @default.
• W2171879002 countsByYear W21718790022012 @default.
• W2171879002 countsByYear W21718790022015 @default.
• W2171879002 countsByYear W21718790022016 @default.
• W2171879002 countsByYear W21718790022017 @default.
• W2171879002 countsByYear W21718790022019 @default.
• W2171879002 countsByYear W21718790022022 @default.
• W2171879002 crossrefType "journal-article" @default.
• W2171879002 hasAuthorship W2171879002A5013601337 @default.
• W2171879002 hasAuthorship W2171879002A5013927834 @default.
• W2171879002 hasAuthorship W2171879002A5021661618 @default.
• W2171879002 hasAuthorship W2171879002A5026788596 @default.
• W2171879002 hasAuthorship W2171879002A5038406743 @default.
• W2171879002 hasAuthorship W2171879002A5048166383 @default.
• W2171879002 hasAuthorship W2171879002A5054994372 @default.
• W2171879002 hasAuthorship W2171879002A5057664407 @default.
• W2171879002 hasAuthorship W2171879002A5069360564 @default.
• W2171879002 hasAuthorship W2171879002A5076249309 @default.
• W2171879002 hasConcept C121608353 @default.
• W2171879002 hasConcept C126322002 @default.
• W2171879002 hasConcept C142724271 @default.
• W2171879002 hasConcept C178790620 @default.
• W2171879002 hasConcept C185592680 @default.
• W2171879002 hasConcept C18823058 @default.
• W2171879002 hasConcept C2775934546 @default.
• W2171879002 hasConcept C2776256026 @default.
• W2171879002 hasConcept C2777405583 @default.
• W2171879002 hasConcept C2777563447 @default.
• W2171879002 hasConcept C2777658100 @default.
• W2171879002 hasConcept C2777714996 @default.
• W2171879002 hasConcept C2781182431 @default.
• W2171879002 hasConcept C502942594 @default.
• W2171879002 hasConcept C71924100 @default.
• W2171879002 hasConceptScore W2171879002C121608353 @default.
• W2171879002 hasConceptScore W2171879002C126322002 @default.
• W2171879002 hasConceptScore W2171879002C142724271 @default.
• W2171879002 hasConceptScore W2171879002C178790620 @default.
• W2171879002 hasConceptScore W2171879002C185592680 @default.
• W2171879002 hasConceptScore W2171879002C18823058 @default.
• W2171879002 hasConceptScore W2171879002C2775934546 @default.
• W2171879002 hasConceptScore W2171879002C2776256026 @default.
• W2171879002 hasConceptScore W2171879002C2777405583 @default.
• W2171879002 hasConceptScore W2171879002C2777563447 @default.
• W2171879002 hasConceptScore W2171879002C2777658100 @default.
• W2171879002 hasConceptScore W2171879002C2777714996 @default.
• W2171879002 hasConceptScore W2171879002C2781182431 @default.
• W2171879002 hasConceptScore W2171879002C502942594 @default.
• W2171879002 hasConceptScore W2171879002C71924100 @default.
• W2171879002 hasIssue "2" @default.
• W2171879002 hasLocation W21718790021 @default.
• W2171879002 hasLocation W21718790022 @default.
• W2171879002 hasOpenAccess W2171879002 @default.
• W2171879002 hasPrimaryLocation W21718790021 @default.
• W2171879002 hasRelatedWork W1969927172 @default.
• W2171879002 hasRelatedWork W2364779800 @default.
• W2171879002 hasRelatedWork W2377056512 @default.
• W2171879002 hasRelatedWork W2383517012 @default.
• W2171879002 hasRelatedWork W2515088231 @default.
• W2171879002 hasRelatedWork W2562771216 @default.

• next