Matches in SemOpenAlex for { <https://semopenalex.org/work/W2171900593> ?p ?o ?g. }
- W2171900593 endingPage "602" @default.
- W2171900593 startingPage "597" @default.
- W2171900593 abstract "Hepatic encephalopathy (HE) is a neuropsychiatric syndrome resulting from liver failure. In the present study, we aimed to standardize an animal model of HE induced by thioacetamide (TAA) in C57BL/6 mice evaluating behavioral symptoms in association with liver damage and alterations in neurotransmitter release.HE was induced by an intraperitoneal single dose of TAA (200 mg/kg, 600 mg/kg or 1,200 mg/kg). Behavioral symptoms were evaluated using the SHIRPA battery. Liver damage was confirmed by histopathological analysis. The glutamate release was measured using fluorimetric assay.The neuropsychiatric state, motor behavior and reflex and sensory functions were significantly altered in the group receiving 600 mg/kg of TAA. Biochemical analysis revealed an increase in the glutamate release in the cerebral cortex of HE mice.HE induced by 600 mg/kg TAA injection in C57BL/6 mice seems to be a suitable model to investigate the pathogenesis and clinical disorders of HE." @default.
- W2171900593 created "2016-06-24" @default.
- W2171900593 creator A5005040503 @default.
- W2171900593 creator A5010992910 @default.
- W2171900593 creator A5028052126 @default.
- W2171900593 creator A5032503259 @default.
- W2171900593 creator A5057696126 @default.
- W2171900593 creator A5064363926 @default.
- W2171900593 creator A5076069194 @default.
- W2171900593 creator A5080449763 @default.
- W2171900593 date "2010-08-01" @default.
- W2171900593 modified "2023-10-06" @default.
- W2171900593 title "A thioacetamide-induced hepatic encephalopathy model in C57BL/6 mice: a behavioral and neurochemical study" @default.
- W2171900593 cites W1582605993 @default.
- W2171900593 cites W1594663117 @default.
- W2171900593 cites W1695353284 @default.
- W2171900593 cites W1982049192 @default.
- W2171900593 cites W1982807202 @default.
- W2171900593 cites W1983708132 @default.
- W2171900593 cites W1985108110 @default.
- W2171900593 cites W2001623639 @default.
- W2171900593 cites W2013666305 @default.
- W2171900593 cites W2031185073 @default.
- W2171900593 cites W2033236189 @default.
- W2171900593 cites W2035115516 @default.
- W2171900593 cites W2035519022 @default.
- W2171900593 cites W2062108200 @default.
- W2171900593 cites W2062444001 @default.
- W2171900593 cites W2068505005 @default.
- W2171900593 cites W2077449299 @default.
- W2171900593 cites W2078328243 @default.
- W2171900593 cites W2084411104 @default.
- W2171900593 cites W2133505259 @default.
- W2171900593 cites W2146648310 @default.
- W2171900593 cites W2165224523 @default.
- W2171900593 cites W2165943471 @default.
- W2171900593 cites W2217238653 @default.
- W2171900593 cites W2326349448 @default.
- W2171900593 cites W2338911760 @default.
- W2171900593 cites W241229272 @default.
- W2171900593 doi "https://doi.org/10.1590/s0004-282x2010000400022" @default.
- W2171900593 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20730316" @default.
- W2171900593 hasPublicationYear "2010" @default.
- W2171900593 type Work @default.
- W2171900593 sameAs 2171900593 @default.
- W2171900593 citedByCount "23" @default.
- W2171900593 countsByYear W21719005932012 @default.
- W2171900593 countsByYear W21719005932013 @default.
- W2171900593 countsByYear W21719005932014 @default.
- W2171900593 countsByYear W21719005932015 @default.
- W2171900593 countsByYear W21719005932018 @default.
- W2171900593 countsByYear W21719005932019 @default.
- W2171900593 countsByYear W21719005932021 @default.
- W2171900593 countsByYear W21719005932022 @default.
- W2171900593 crossrefType "journal-article" @default.
- W2171900593 hasAuthorship W2171900593A5005040503 @default.
- W2171900593 hasAuthorship W2171900593A5010992910 @default.
- W2171900593 hasAuthorship W2171900593A5028052126 @default.
- W2171900593 hasAuthorship W2171900593A5032503259 @default.
- W2171900593 hasAuthorship W2171900593A5057696126 @default.
- W2171900593 hasAuthorship W2171900593A5064363926 @default.
- W2171900593 hasAuthorship W2171900593A5076069194 @default.
- W2171900593 hasAuthorship W2171900593A5080449763 @default.
- W2171900593 hasBestOaLocation W21719005931 @default.
- W2171900593 hasConcept C126322002 @default.
- W2171900593 hasConcept C134018914 @default.
- W2171900593 hasConcept C170493617 @default.
- W2171900593 hasConcept C25876315 @default.
- W2171900593 hasConcept C2776219046 @default.
- W2171900593 hasConcept C2777214474 @default.
- W2171900593 hasConcept C2778117688 @default.
- W2171900593 hasConcept C2778621155 @default.
- W2171900593 hasConcept C2780159080 @default.
- W2171900593 hasConcept C2780325230 @default.
- W2171900593 hasConcept C2781057625 @default.
- W2171900593 hasConcept C529278444 @default.
- W2171900593 hasConcept C61174792 @default.
- W2171900593 hasConcept C71924100 @default.
- W2171900593 hasConcept C98274493 @default.
- W2171900593 hasConceptScore W2171900593C126322002 @default.
- W2171900593 hasConceptScore W2171900593C134018914 @default.
- W2171900593 hasConceptScore W2171900593C170493617 @default.
- W2171900593 hasConceptScore W2171900593C25876315 @default.
- W2171900593 hasConceptScore W2171900593C2776219046 @default.
- W2171900593 hasConceptScore W2171900593C2777214474 @default.
- W2171900593 hasConceptScore W2171900593C2778117688 @default.
- W2171900593 hasConceptScore W2171900593C2778621155 @default.
- W2171900593 hasConceptScore W2171900593C2780159080 @default.
- W2171900593 hasConceptScore W2171900593C2780325230 @default.
- W2171900593 hasConceptScore W2171900593C2781057625 @default.
- W2171900593 hasConceptScore W2171900593C529278444 @default.
- W2171900593 hasConceptScore W2171900593C61174792 @default.
- W2171900593 hasConceptScore W2171900593C71924100 @default.
- W2171900593 hasConceptScore W2171900593C98274493 @default.
- W2171900593 hasIssue "4" @default.
- W2171900593 hasLocation W21719005931 @default.
- W2171900593 hasLocation W21719005932 @default.
- W2171900593 hasLocation W21719005933 @default.