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- W2172021496 abstract "In addition to the well-defined hereditary primary ichthyoses, many sporadic or less well-defined keratinization disorders with or without systemic manifestations have been reported. Herein we describe ichthyosiform dermatosis associated with type 2 diabetes mellitus.The patients were members of a large Arab family with heavy consanguinity. Eighteen members were affected with a variously severe scaly disorder. They showed migratory polycyclic keratotic scaly plaques evolving into diffuse generalized scaling or complete remission. Acanthosis nigricans-like lesions were also noted, and there was an association with type 2 diabetes mellitus. A scarcity of intercorneocyte lamellae and reduction in lamellar body contents were observed.We could not find a report of a similar dermatosis. Furthermore, an association between ichthyosis and diabetes has not been documented. Therefore, we believe that this may constitute a new entity." @default.
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- W2172021496 date "1999-10-01" @default.
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- W2172021496 title "Migratory Ichthyosiform Dermatosis With Type 2 Diabetes Mellitus and Insulin Resistance" @default.
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- W2172021496 doi "https://doi.org/10.1001/archderm.135.10.1237" @default.
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