Matches in SemOpenAlex for { <https://semopenalex.org/work/W2172023350> ?p ?o ?g. }
- W2172023350 endingPage "984" @default.
- W2172023350 startingPage "978" @default.
- W2172023350 abstract "To compare the effects of alpha-linolenic acid (ALA, C18:3n-3) to those of eicosapentaenoic acid (EPA, C20:5n-3) plus docosahexaenoic acid (DHA, C22:6n-3) on cardiovascular risk markers in healthy elderly subjects. A randomized double-blind nutritional intervention study. Department of Human Biology, Maastricht University, the Netherlands. Thirty-seven mildly hypercholesterolemic subjects, 14 men and 23 women aged between 60 and 78 years. During a run-in period of 3 weeks, subjects consumed an oleic acid-rich diet. The following 6 weeks, 10 subjects remained on the control diet, 13 subjects consumed an ALA-rich diet (6.8 g/day) and 14 subjects an EPA/DHA-rich diet (1.05 g EPA/day+0.55 g DHA/day). Both n-3 fatty acid diets did not change concentrations of total-cholesterol, LDL-cholesterol, HDL-cholesterol, triacylglycerol and apoA-1 when compared with the oleic acid-rich diet. However, after the EPA/DHA-rich diet, LDL-cholesterol increased by 0.39 mmol/l (P=0.0323, 95% CI (0.030, 0.780 mmol/l)) when compared with the ALA-rich diet. Intake of EPA/DHA also increased apoB concentrations by 14 mg/dl (P=0.0031, 95% CI (4, 23 mg/dl)) and 12 mg/dl (P=0.005, 95% CI (3, 21 mg/dl)) versus the oleic acid and ALA-rich diet, respectively. Except for an EPA/DHA-induced increase in tissue factor pathway inhibitor (TFPI) of 14.6% (P=0.0184 versus ALA diet, 95% CI (1.5, 18.3%)), changes in markers of hemostasis and endothelial integrity did not reach statistical significance following consumption of the two n-3 fatty acid diets. In healthy elderly subjects, ALA might affect concentrations of LDL-cholesterol and apoB more favorably than EPA/DHA, whereas EPA/DHA seems to affect TFPI more beneficially." @default.
- W2172023350 created "2016-06-24" @default.
- W2172023350 creator A5006945105 @default.
- W2172023350 creator A5030716521 @default.
- W2172023350 date "2006-02-15" @default.
- W2172023350 modified "2023-10-17" @default.
- W2172023350 title "Effects of alpha-linolenic acid versus those of EPA/DHA on cardiovascular risk markers in healthy elderly subjects" @default.
- W2172023350 cites W1814285964 @default.
- W2172023350 cites W1872982664 @default.
- W2172023350 cites W1910588805 @default.
- W2172023350 cites W1914089044 @default.
- W2172023350 cites W1946799893 @default.
- W2172023350 cites W1978039741 @default.
- W2172023350 cites W1990660916 @default.
- W2172023350 cites W2004311965 @default.
- W2172023350 cites W2008292459 @default.
- W2172023350 cites W2023667174 @default.
- W2172023350 cites W2026904223 @default.
- W2172023350 cites W2028233831 @default.
- W2172023350 cites W2030042443 @default.
- W2172023350 cites W2044288369 @default.
- W2172023350 cites W2050817043 @default.
- W2172023350 cites W2079493234 @default.
- W2172023350 cites W2085980486 @default.
- W2172023350 cites W2101165462 @default.
- W2172023350 cites W2103242651 @default.
- W2172023350 cites W2107928904 @default.
- W2172023350 cites W2116404316 @default.
- W2172023350 cites W2126056518 @default.
- W2172023350 cites W2128568125 @default.
- W2172023350 cites W2133293840 @default.
- W2172023350 cites W2138419705 @default.
- W2172023350 cites W2143431760 @default.
- W2172023350 cites W2145193708 @default.
- W2172023350 cites W2145294481 @default.
- W2172023350 cites W2151821320 @default.
- W2172023350 cites W2165356488 @default.
- W2172023350 cites W2192223169 @default.
- W2172023350 cites W2285264705 @default.
- W2172023350 cites W2411933642 @default.
- W2172023350 cites W4300097062 @default.
- W2172023350 doi "https://doi.org/10.1038/sj.ejcn.1602408" @default.
- W2172023350 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16482073" @default.
- W2172023350 hasPublicationYear "2006" @default.
- W2172023350 type Work @default.
- W2172023350 sameAs 2172023350 @default.
- W2172023350 citedByCount "52" @default.
- W2172023350 countsByYear W21720233502012 @default.
- W2172023350 countsByYear W21720233502013 @default.
- W2172023350 countsByYear W21720233502014 @default.
- W2172023350 countsByYear W21720233502015 @default.
- W2172023350 countsByYear W21720233502016 @default.
- W2172023350 countsByYear W21720233502017 @default.
- W2172023350 countsByYear W21720233502018 @default.
- W2172023350 countsByYear W21720233502019 @default.
- W2172023350 countsByYear W21720233502020 @default.
- W2172023350 countsByYear W21720233502021 @default.
- W2172023350 countsByYear W21720233502022 @default.
- W2172023350 countsByYear W21720233502023 @default.
- W2172023350 crossrefType "journal-article" @default.
- W2172023350 hasAuthorship W2172023350A5006945105 @default.
- W2172023350 hasAuthorship W2172023350A5030716521 @default.
- W2172023350 hasBestOaLocation W21720233501 @default.
- W2172023350 hasConcept C126322002 @default.
- W2172023350 hasConcept C134018914 @default.
- W2172023350 hasConcept C185592680 @default.
- W2172023350 hasConcept C19038510 @default.
- W2172023350 hasConcept C2776091944 @default.
- W2172023350 hasConcept C2776176469 @default.
- W2172023350 hasConcept C2777171753 @default.
- W2172023350 hasConcept C2777686832 @default.
- W2172023350 hasConcept C2778163477 @default.
- W2172023350 hasConcept C2780809830 @default.
- W2172023350 hasConcept C2781403372 @default.
- W2172023350 hasConcept C31903555 @default.
- W2172023350 hasConcept C543025807 @default.
- W2172023350 hasConcept C55493867 @default.
- W2172023350 hasConcept C62746215 @default.
- W2172023350 hasConcept C71924100 @default.
- W2172023350 hasConceptScore W2172023350C126322002 @default.
- W2172023350 hasConceptScore W2172023350C134018914 @default.
- W2172023350 hasConceptScore W2172023350C185592680 @default.
- W2172023350 hasConceptScore W2172023350C19038510 @default.
- W2172023350 hasConceptScore W2172023350C2776091944 @default.
- W2172023350 hasConceptScore W2172023350C2776176469 @default.
- W2172023350 hasConceptScore W2172023350C2777171753 @default.
- W2172023350 hasConceptScore W2172023350C2777686832 @default.
- W2172023350 hasConceptScore W2172023350C2778163477 @default.
- W2172023350 hasConceptScore W2172023350C2780809830 @default.
- W2172023350 hasConceptScore W2172023350C2781403372 @default.
- W2172023350 hasConceptScore W2172023350C31903555 @default.
- W2172023350 hasConceptScore W2172023350C543025807 @default.
- W2172023350 hasConceptScore W2172023350C55493867 @default.
- W2172023350 hasConceptScore W2172023350C62746215 @default.
- W2172023350 hasConceptScore W2172023350C71924100 @default.
- W2172023350 hasIssue "8" @default.
- W2172023350 hasLocation W21720233501 @default.
- W2172023350 hasLocation W21720233502 @default.