Matches in SemOpenAlex for { <https://semopenalex.org/work/W2172027872> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2172027872 endingPage "331" @default.
- W2172027872 startingPage "331" @default.
- W2172027872 abstract "Background: The objective was to evaluate the analgesic activity of irbesartan in albino mice. Methods: Swiss albino mice weighing 25-30 g of either sex were selected for the study. Six animals were allocated to each experimental group. The control group received normal saline (25 ml/kg, p.o.), standard group received pentazocine (10mg/kg, intraperitonial [i.p.]) and test group received irbesartan (20 mg/kg, p.o.). The above drugs were administered 1 hr prior to the experiments. In case of visceral pain model 0.6% acetic acid was given i.p. 30 mins prior to the experiment to induce writhing, in thermal pain model pretreated mice were placed on Eddy’s Hotplate maintained at 55°C and in mechanical stimulus pain model an artery clip was clamped at the base of the tail of pretreated mice. Decrease in total number of writhes in acetic acid induced writhing model and delay in reaction time in both Eddy’s hot plate and Tail clip method denoted analgesic activity respectively. Results: The test drug significantly decreased the total number of writhes in acetic acid induced writhing model in mice. The percentage inhibition of writhing was significant which was 84.35% in the standard group and 59.24% in the test group. The test drug significantly delayed the reaction time in both Eddy’s hot plate and tail clip method when compared to control group and standard group. Percentage increase in latency period when compared to standard drug was significant and measured 73.11% and 64.31% at 60 min in both Eddy’s hot plate and tail clip method, respectively. Conclusion: Irbesartan exhibits analgesic activity in albino mice." @default.
- W2172027872 created "2016-06-24" @default.
- W2172027872 creator A5000314056 @default.
- W2172027872 creator A5003149898 @default.
- W2172027872 creator A5045332061 @default.
- W2172027872 creator A5069332872 @default.
- W2172027872 creator A5085596895 @default.
- W2172027872 creator A5087231709 @default.
- W2172027872 date "2014-01-01" @default.
- W2172027872 modified "2023-10-01" @default.
- W2172027872 title "Evaluation of analgesic activity of irbesartan in albino mice" @default.
- W2172027872 doi "https://doi.org/10.5455/2319-2003.ijbcp20140414" @default.
- W2172027872 hasPublicationYear "2014" @default.
- W2172027872 type Work @default.
- W2172027872 sameAs 2172027872 @default.
- W2172027872 citedByCount "0" @default.
- W2172027872 crossrefType "journal-article" @default.
- W2172027872 hasAuthorship W2172027872A5000314056 @default.
- W2172027872 hasAuthorship W2172027872A5003149898 @default.
- W2172027872 hasAuthorship W2172027872A5045332061 @default.
- W2172027872 hasAuthorship W2172027872A5069332872 @default.
- W2172027872 hasAuthorship W2172027872A5085596895 @default.
- W2172027872 hasAuthorship W2172027872A5087231709 @default.
- W2172027872 hasBestOaLocation W21720278721 @default.
- W2172027872 hasConcept C126322002 @default.
- W2172027872 hasConcept C127413603 @default.
- W2172027872 hasConcept C185592680 @default.
- W2172027872 hasConcept C2776673659 @default.
- W2172027872 hasConcept C2777397205 @default.
- W2172027872 hasConcept C2780259554 @default.
- W2172027872 hasConcept C2780802079 @default.
- W2172027872 hasConcept C2780820201 @default.
- W2172027872 hasConcept C2993566434 @default.
- W2172027872 hasConcept C42219234 @default.
- W2172027872 hasConcept C55493867 @default.
- W2172027872 hasConcept C71924100 @default.
- W2172027872 hasConcept C78519656 @default.
- W2172027872 hasConcept C84393581 @default.
- W2172027872 hasConcept C98274493 @default.
- W2172027872 hasConceptScore W2172027872C126322002 @default.
- W2172027872 hasConceptScore W2172027872C127413603 @default.
- W2172027872 hasConceptScore W2172027872C185592680 @default.
- W2172027872 hasConceptScore W2172027872C2776673659 @default.
- W2172027872 hasConceptScore W2172027872C2777397205 @default.
- W2172027872 hasConceptScore W2172027872C2780259554 @default.
- W2172027872 hasConceptScore W2172027872C2780802079 @default.
- W2172027872 hasConceptScore W2172027872C2780820201 @default.
- W2172027872 hasConceptScore W2172027872C2993566434 @default.
- W2172027872 hasConceptScore W2172027872C42219234 @default.
- W2172027872 hasConceptScore W2172027872C55493867 @default.
- W2172027872 hasConceptScore W2172027872C71924100 @default.
- W2172027872 hasConceptScore W2172027872C78519656 @default.
- W2172027872 hasConceptScore W2172027872C84393581 @default.
- W2172027872 hasConceptScore W2172027872C98274493 @default.
- W2172027872 hasIssue "2" @default.
- W2172027872 hasLocation W21720278721 @default.
- W2172027872 hasOpenAccess W2172027872 @default.
- W2172027872 hasPrimaryLocation W21720278721 @default.
- W2172027872 hasRelatedWork W2026651181 @default.
- W2172027872 hasRelatedWork W2164854576 @default.
- W2172027872 hasRelatedWork W2187528199 @default.
- W2172027872 hasRelatedWork W2330551678 @default.
- W2172027872 hasRelatedWork W2347600984 @default.
- W2172027872 hasRelatedWork W2362397980 @default.
- W2172027872 hasRelatedWork W2366365012 @default.
- W2172027872 hasRelatedWork W2373385748 @default.
- W2172027872 hasRelatedWork W2376273889 @default.
- W2172027872 hasRelatedWork W2384932904 @default.
- W2172027872 hasRelatedWork W2387708238 @default.
- W2172027872 hasRelatedWork W2390523611 @default.
- W2172027872 hasRelatedWork W2391158761 @default.
- W2172027872 hasRelatedWork W2524012268 @default.
- W2172027872 hasRelatedWork W2621512493 @default.
- W2172027872 hasRelatedWork W2806635719 @default.
- W2172027872 hasRelatedWork W2886226200 @default.
- W2172027872 hasRelatedWork W3029186870 @default.
- W2172027872 hasRelatedWork W3031271243 @default.
- W2172027872 hasRelatedWork W3146403966 @default.
- W2172027872 hasVolume "3" @default.
- W2172027872 isParatext "false" @default.
- W2172027872 isRetracted "false" @default.
- W2172027872 magId "2172027872" @default.
- W2172027872 workType "article" @default.