FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2172112723> ?p ?o ?g. }

• W2172112723 endingPage "551" @default.
• W2172112723 startingPage "543" @default.
• W2172112723 abstract "Background. Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry accurately identifies both selected bacteria and bacteria in select clinical situations. It has not been evaluated for routine use in the clinic. Methods. We prospectively analyzed routine MALDI-TOF mass spectrometry identification in parallel with conventional phenotypic identification of bacteria regardless of phylum or source of isolation. Discrepancies were resolved by 16S ribosomal RNA and rpo B gene sequence-based molecular identification. Colonies (4 spots per isolate directly deposited on the MALDI-TOF plate) were analyzed using an Autoflex II Bruker Daltonik mass spectrometer. Peptidic spectra were compared with the Bruker BioTyper database, version 2.0, and the identification score was noted. Delays and costs of identification were measured. Results. Of 1660 bacterial isolates analyzed, 95.4% were correctly identified by MALDI-TOF mass spectrometry; 84.1% were identified at the species level, and 11.3% were identified at the genus level. In most cases, absence of identification (2.8% of isolates) and erroneous identification (1.7% of isolates) were due to improper database entries. Accurate MALDI-TOF mass spectrometry identification was significantly correlated with having 10 reference spectra in the database (P=.01). The mean time required for MALDI-TOF mass spectrometry identification of 1 isolate was 6 minutes for an estimated 22%–32% cost of current methods of identification. Conclusions. MALDI-TOF mass spectrometry is a cost-effective, accurate method for routine identification of bacterial isolates in <1 h using a database comprising ⩾10 reference spectra per bacterial species and a ⩾1.9 identification score (Brucker system). It may replace Gram staining and biochemical identification in the near future." @default.
• W2172112723 created "2016-06-24" @default.
• W2172112723 creator A5012670349 @default.
• W2172112723 creator A5023619971 @default.
• W2172112723 creator A5029746537 @default.
• W2172112723 creator A5038418925 @default.
• W2172112723 creator A5064706278 @default.
• W2172112723 creator A5072255773 @default.
• W2172112723 creator A5074730004 @default.
• W2172112723 date "2009-08-15" @default.
• W2172112723 modified "2023-10-15" @default.
• W2172112723 title "Ongoing Revolution in Bacteriology: Routine Identification of Bacteria by Matrix‐Assisted Laser Desorption Ionization Time‐of‐Flight Mass Spectrometry" @default.
• W2172112723 cites W1582757057 @default.
• W2172112723 cites W1965366579 @default.
• W2172112723 cites W1975771011 @default.
• W2172112723 cites W1989173936 @default.
• W2172112723 cites W1989603874 @default.
• W2172112723 cites W1995649556 @default.
• W2172112723 cites W1996750397 @default.
• W2172112723 cites W2010928292 @default.
• W2172112723 cites W2014820375 @default.
• W2172112723 cites W2027825520 @default.
• W2172112723 cites W2030530116 @default.
• W2172112723 cites W2034850779 @default.
• W2172112723 cites W2036423057 @default.
• W2172112723 cites W2037859787 @default.
• W2172112723 cites W2046256669 @default.
• W2172112723 cites W2046845578 @default.
• W2172112723 cites W2050152399 @default.
• W2172112723 cites W2055679208 @default.
• W2172112723 cites W2057847565 @default.
• W2172112723 cites W2063576289 @default.
• W2172112723 cites W2071682026 @default.
• W2172112723 cites W2073670190 @default.
• W2172112723 cites W2076563754 @default.
• W2172112723 cites W2080212641 @default.
• W2172112723 cites W2081976622 @default.
• W2172112723 cites W2088856847 @default.
• W2172112723 cites W2089046621 @default.
• W2172112723 cites W2090482417 @default.
• W2172112723 cites W2097410180 @default.
• W2172112723 cites W2100117600 @default.
• W2172112723 cites W2101183780 @default.
• W2172112723 cites W2109882926 @default.
• W2172112723 cites W2114496828 @default.
• W2172112723 cites W2114991485 @default.
• W2172112723 cites W2120630118 @default.
• W2172112723 cites W2120979806 @default.
• W2172112723 cites W2121794620 @default.
• W2172112723 cites W2129761524 @default.
• W2172112723 cites W2131574268 @default.
• W2172112723 cites W2131970571 @default.
• W2172112723 cites W2134098191 @default.
• W2172112723 cites W2136687836 @default.
• W2172112723 cites W2138676971 @default.
• W2172112723 cites W2150068612 @default.
• W2172112723 cites W2150595816 @default.
• W2172112723 cites W2153103702 @default.
• W2172112723 cites W2164212998 @default.
• W2172112723 cites W2166785990 @default.
• W2172112723 cites W2170058499 @default.
• W2172112723 cites W2923611692 @default.
• W2172112723 doi "https://doi.org/10.1086/600885" @default.
• W2172112723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19583519" @default.
• W2172112723 hasPublicationYear "2009" @default.
• W2172112723 type Work @default.
• W2172112723 sameAs 2172112723 @default.
• W2172112723 citedByCount "1624" @default.
• W2172112723 countsByYear W21721127232012 @default.
• W2172112723 countsByYear W21721127232013 @default.
• W2172112723 countsByYear W21721127232014 @default.
• W2172112723 countsByYear W21721127232015 @default.
• W2172112723 countsByYear W21721127232016 @default.
• W2172112723 countsByYear W21721127232017 @default.
• W2172112723 countsByYear W21721127232018 @default.
• W2172112723 countsByYear W21721127232019 @default.
• W2172112723 countsByYear W21721127232020 @default.
• W2172112723 countsByYear W21721127232021 @default.
• W2172112723 countsByYear W21721127232022 @default.
• W2172112723 countsByYear W21721127232023 @default.
• W2172112723 crossrefType "journal-article" @default.
• W2172112723 hasAuthorship W2172112723A5012670349 @default.
• W2172112723 hasAuthorship W2172112723A5023619971 @default.
• W2172112723 hasAuthorship W2172112723A5029746537 @default.
• W2172112723 hasAuthorship W2172112723A5038418925 @default.
• W2172112723 hasAuthorship W2172112723A5064706278 @default.
• W2172112723 hasAuthorship W2172112723A5072255773 @default.
• W2172112723 hasAuthorship W2172112723A5074730004 @default.
• W2172112723 hasConcept C116834253 @default.
• W2172112723 hasConcept C145148216 @default.
• W2172112723 hasConcept C150394285 @default.
• W2172112723 hasConcept C162356407 @default.
• W2172112723 hasConcept C162711632 @default.
• W2172112723 hasConcept C16291436 @default.
• W2172112723 hasConcept C178790620 @default.
• W2172112723 hasConcept C185592680 @default.
• W2172112723 hasConcept C198291218 @default.
• W2172112723 hasConcept C40325409 @default.

• next