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• W2172201122 abstract "The cloning of the G protein-coupled, extracellular calcium (Ca(2+)o)-sensing receptor (CaR) has identified a central mediator of the mechanism governing systemic Ca(2+)o homeostasis. This system enables organisms to adapt successfully to wide variations in dietary Ca(2+)o intake while maintaining near constancy of Ca(2+)o. Whereas discussions of Ca(2+)o homeostasis have generally focused on the key role of Ca(2+)o-elicited changes in parathyroid hormone secretion, the presence of the CaRs in effector tissues of this system enables direct regulation of processes (e.g. renal tubular Ca(2+) reabsorption and possibly bone formation and resorption) that add additional layers of homeostatic control. As we understand more about how the CaR regulates these tissues, we may find that it participates in other processes relevant to mineral ion homeostasis, including the control of the 1-hydroxylation and activation of vitamin D3 or reabsorption of phosphate in the renal proximal tubule. Regardless, the remarkable sensitivity of the CaR to small changes in Ca(2+)o allows adjustments in the response of the Ca(2+)o homeostatic system to increases or decreases in the intake of dietary Ca(2+), for instance, that cause barely detectable alterations in Ca(2+)o. Furthermore, the CaR likely participates in coordinating interactions among several different homeostatic control systems (including those for water, Mg(2+)o, Na(+), extracellular volume, and/or blood pressure), despite the fact that these systems are often considered to function largely independently of mineral ion metabolism." @default.
• W2172201122 created "2016-06-24" @default.
• W2172201122 creator A5038281830 @default.
• W2172201122 date "2000-07-01" @default.
• W2172201122 modified "2023-10-11" @default.
• W2172201122 title "T<scp>HE</scp> E<scp>XTRACELLULAR</scp> Ca²⁺-S<scp>ENSING</scp> R<scp>ECEPTOR</scp>: Central Mediator of Systemic Calcium Homeostasis" @default.
• W2172201122 cites W1503505561 @default.
• W2172201122 cites W1578432561 @default.
• W2172201122 cites W1599670156 @default.
• W2172201122 cites W1753116283 @default.
• W2172201122 cites W1853215604 @default.
• W2172201122 cites W1882996137 @default.
• W2172201122 cites W1966419963 @default.
• W2172201122 cites W1969201146 @default.
• W2172201122 cites W1971647071 @default.
• W2172201122 cites W1972065681 @default.
• W2172201122 cites W1972376675 @default.
• W2172201122 cites W1972864808 @default.
• W2172201122 cites W1973490702 @default.
• W2172201122 cites W1975367389 @default.
• W2172201122 cites W1977019491 @default.
• W2172201122 cites W1984252569 @default.
• W2172201122 cites W1987972099 @default.
• W2172201122 cites W1993191224 @default.
• W2172201122 cites W1998163197 @default.
• W2172201122 cites W2000227813 @default.
• W2172201122 cites W2001523744 @default.
• W2172201122 cites W2002288024 @default.
• W2172201122 cites W2003197654 @default.
• W2172201122 cites W2003265581 @default.
• W2172201122 cites W2005637545 @default.
• W2172201122 cites W2006020017 @default.
• W2172201122 cites W2007322941 @default.
• W2172201122 cites W2007453290 @default.
• W2172201122 cites W2009441758 @default.
• W2172201122 cites W2009672068 @default.
• W2172201122 cites W2009783633 @default.
• W2172201122 cites W2010824345 @default.
• W2172201122 cites W2011539758 @default.
• W2172201122 cites W2012056124 @default.
• W2172201122 cites W2016818162 @default.
• W2172201122 cites W2017107129 @default.
• W2172201122 cites W2026624187 @default.
• W2172201122 cites W2027466826 @default.
• W2172201122 cites W2029960493 @default.
• W2172201122 cites W2030363901 @default.
• W2172201122 cites W2034085896 @default.
• W2172201122 cites W2035258502 @default.
• W2172201122 cites W2035995595 @default.
• W2172201122 cites W2038261146 @default.
• W2172201122 cites W2042484533 @default.
• W2172201122 cites W2047344940 @default.
• W2172201122 cites W2047907147 @default.
• W2172201122 cites W2049684139 @default.
• W2172201122 cites W2050419480 @default.
• W2172201122 cites W2056444232 @default.
• W2172201122 cites W2061281426 @default.
• W2172201122 cites W2062491158 @default.
• W2172201122 cites W2063146137 @default.
• W2172201122 cites W2065390805 @default.
• W2172201122 cites W2067466593 @default.
• W2172201122 cites W2071855678 @default.
• W2172201122 cites W2072406610 @default.
• W2172201122 cites W2074098367 @default.
• W2172201122 cites W2076606204 @default.
• W2172201122 cites W2077973233 @default.
• W2172201122 cites W2078103041 @default.
• W2172201122 cites W2078643685 @default.
• W2172201122 cites W2081730365 @default.
• W2172201122 cites W2083169698 @default.
• W2172201122 cites W2084671833 @default.
• W2172201122 cites W2086766564 @default.
• W2172201122 cites W2089464041 @default.
• W2172201122 cites W2095233918 @default.
• W2172201122 cites W2102108938 @default.
• W2172201122 cites W2107745544 @default.
• W2172201122 cites W2113376778 @default.
• W2172201122 cites W2113902080 @default.
• W2172201122 cites W2120038848 @default.
• W2172201122 cites W2130137701 @default.
• W2172201122 cites W2132094269 @default.
• W2172201122 cites W2133024873 @default.
• W2172201122 cites W2136372143 @default.
• W2172201122 cites W2149959147 @default.
• W2172201122 cites W2153170303 @default.
• W2172201122 cites W2167767264 @default.
• W2172201122 cites W2170949021 @default.
• W2172201122 cites W2178569498 @default.
• W2172201122 cites W2199386566 @default.
• W2172201122 cites W2213999600 @default.
• W2172201122 cites W2321505964 @default.
• W2172201122 cites W2337614773 @default.
• W2172201122 cites W2497998316 @default.
• W2172201122 cites W4233743612 @default.
• W2172201122 cites W4238498928 @default.
• W2172201122 cites W4239048444 @default.
• W2172201122 cites W4239125062 @default.
• W2172201122 cites W4240001022 @default.

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