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- W2172267938 abstract "To measure and evaluate the health-related quality of life (HRQOL) in patients with cutaneous T-cell lymphoma (CTCL), a visible cutaneous malignancy that may have a profound effect on patients' lives.Monocenter, cross-sectional study.The Skin Oncology Program, Department of Dermatology, and the Photopheresis Unit of Boston Medical Center.A total of 22 adult patients with confirmed CTCL.(1) Evaluation of general oncologic and skin disease-specific HRQOL using, respectively, the Functional Assessment of Cancer Therapy-General (FACT-G) and Skindex-29 profiles; (2) assessment of HRQOL association with disease stage (early stage, IA-IIA; late stage, IIB-IVB).Patients with more advanced CTCL stages reported more effects on general health (FACT-G), particularly in the physical, emotional, and functional domains (P < .05). Patients with early-stage CTCL reported better skin-specific HRQOL overall (Skindex-29; P = .002) and for each specific domain than did patients with late-stage disease. The Skindex-29 scales had high internal consistency, and the confirmatory factor structure was similar to that of previous studies.The HRQOL of patients with CTCL can be evaluated using the Skindex-29 and FACT-G instruments. Patients with more advanced stages of CTCL had lower HRQOL scores." @default.
- W2172267938 created "2016-06-24" @default.
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- W2172267938 date "2005-03-01" @default.
- W2172267938 modified "2023-09-25" @default.
- W2172267938 title "Health-Related Quality-of-Life Assessment in Patients With Cutaneous T-Cell Lymphoma" @default.
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- W2172267938 doi "https://doi.org/10.1001/archderm.141.3.325" @default.
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