Matches in SemOpenAlex for { <https://semopenalex.org/work/W2172290131> ?p ?o ?g. }
- W2172290131 endingPage "6" @default.
- W2172290131 startingPage "1" @default.
- W2172290131 abstract "Decades of research in bioengineering have resulted in the development of many types of 3-dimentional (3D) scaffolds for use as drug delivery systems (DDS) and for tissue regeneration. Scaffolds may be comprised of different natural fibers and synthetic polymers as well as ceramics in order to exert the most beneficial attributes including biocompatibility, biodegradability, structural integrity, cell infiltration and attachment, and neovascularization. Type I collagen scaffolds meet most of these criteria. In addition, type I collagen binds integrins through RGD and non-RGD sites which facilitates cell migration, attachment, and proliferation. Type I collagen scaffolds can be used for bone tissue repair when they are coated with osteogenic proteins such as bone morphogenic protein (BMP) and bone sialoprotein (BSP). BSP, a small integrin-binding ligand N-linked glycoprotein (SIBLING), has osteogenic properties and plays an essential role in bone formation. BSP also mediates mineral deposition, binds type I collagen with high affinity, and binds α v β 3 and α v β 5 integrins which mediate cell signaling. This paper reviews the emerging evidence demonstrating the efficacy of BSP-collagen scaffolds in bone regeneration." @default.
- W2172290131 created "2016-06-24" @default.
- W2172290131 creator A5061684037 @default.
- W2172290131 creator A5073632269 @default.
- W2172290131 creator A5076322374 @default.
- W2172290131 date "2013-01-01" @default.
- W2172290131 modified "2023-10-18" @default.
- W2172290131 title "Collagen Scaffolds in Bone Sialoprotein-Mediated Bone Regeneration" @default.
- W2172290131 cites W1483896637 @default.
- W2172290131 cites W1586020992 @default.
- W2172290131 cites W1965339729 @default.
- W2172290131 cites W1971776337 @default.
- W2172290131 cites W1971908037 @default.
- W2172290131 cites W1981921330 @default.
- W2172290131 cites W1988965035 @default.
- W2172290131 cites W1989307073 @default.
- W2172290131 cites W1996266076 @default.
- W2172290131 cites W2000706451 @default.
- W2172290131 cites W2004847621 @default.
- W2172290131 cites W2006394017 @default.
- W2172290131 cites W2035066110 @default.
- W2172290131 cites W2039019929 @default.
- W2172290131 cites W2050620674 @default.
- W2172290131 cites W2052871444 @default.
- W2172290131 cites W2054627021 @default.
- W2172290131 cites W2055426312 @default.
- W2172290131 cites W2055827549 @default.
- W2172290131 cites W2059993294 @default.
- W2172290131 cites W2060078219 @default.
- W2172290131 cites W2060961719 @default.
- W2172290131 cites W2065039664 @default.
- W2172290131 cites W2065063645 @default.
- W2172290131 cites W2070466054 @default.
- W2172290131 cites W2078238416 @default.
- W2172290131 cites W2091967829 @default.
- W2172290131 cites W2093452004 @default.
- W2172290131 cites W2094855192 @default.
- W2172290131 cites W2102617674 @default.
- W2172290131 cites W2105245659 @default.
- W2172290131 cites W2110119922 @default.
- W2172290131 cites W2111460006 @default.
- W2172290131 cites W2112698502 @default.
- W2172290131 cites W2115041578 @default.
- W2172290131 cites W2125613276 @default.
- W2172290131 cites W2140411306 @default.
- W2172290131 cites W2141871922 @default.
- W2172290131 cites W2145165079 @default.
- W2172290131 cites W2147834652 @default.
- W2172290131 cites W2153532131 @default.
- W2172290131 cites W2154387825 @default.
- W2172290131 cites W2159185781 @default.
- W2172290131 cites W2161162374 @default.
- W2172290131 cites W2165044415 @default.
- W2172290131 cites W2954701605 @default.
- W2172290131 cites W4211200865 @default.
- W2172290131 cites W4230222460 @default.
- W2172290131 cites W4361983513 @default.
- W2172290131 doi "https://doi.org/10.1155/2013/812718" @default.
- W2172290131 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3628497" @default.
- W2172290131 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23653530" @default.
- W2172290131 hasPublicationYear "2013" @default.
- W2172290131 type Work @default.
- W2172290131 sameAs 2172290131 @default.
- W2172290131 citedByCount "65" @default.
- W2172290131 countsByYear W21722901312013 @default.
- W2172290131 countsByYear W21722901312014 @default.
- W2172290131 countsByYear W21722901312015 @default.
- W2172290131 countsByYear W21722901312016 @default.
- W2172290131 countsByYear W21722901312017 @default.
- W2172290131 countsByYear W21722901312018 @default.
- W2172290131 countsByYear W21722901312019 @default.
- W2172290131 countsByYear W21722901312020 @default.
- W2172290131 countsByYear W21722901312021 @default.
- W2172290131 countsByYear W21722901312022 @default.
- W2172290131 countsByYear W21722901312023 @default.
- W2172290131 crossrefType "journal-article" @default.
- W2172290131 hasAuthorship W2172290131A5061684037 @default.
- W2172290131 hasAuthorship W2172290131A5073632269 @default.
- W2172290131 hasAuthorship W2172290131A5076322374 @default.
- W2172290131 hasBestOaLocation W21722901311 @default.
- W2172290131 hasConcept C105702510 @default.
- W2172290131 hasConcept C131075544 @default.
- W2172290131 hasConcept C142724271 @default.
- W2172290131 hasConcept C1491633281 @default.
- W2172290131 hasConcept C160160445 @default.
- W2172290131 hasConcept C171056886 @default.
- W2172290131 hasConcept C181199279 @default.
- W2172290131 hasConcept C185592680 @default.
- W2172290131 hasConcept C195687474 @default.
- W2172290131 hasConcept C2776432469 @default.
- W2172290131 hasConcept C2780644872 @default.
- W2172290131 hasConcept C55493867 @default.
- W2172290131 hasConcept C71924100 @default.
- W2172290131 hasConcept C8337478 @default.
- W2172290131 hasConcept C86803240 @default.
- W2172290131 hasConcept C95444343 @default.
- W2172290131 hasConceptScore W2172290131C105702510 @default.
- W2172290131 hasConceptScore W2172290131C131075544 @default.