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• W2172952877 abstract "Objective To examine the effects of potentially inappropriate medication ( PIM ) use on health care outcomes in elderly individuals using an instrumental variable ( IV ) approach. Data Sources/Study Setting Representative claim data from the universal health insurance program in Taiwan from 2007 to 2010. Study Design We employed a panel study design to examine the relationship between PIM and hospitalization. We applied both the naive generalized estimating equation ( GEE ) model, which controlled for the observed patient and hospital characteristics, and the two‐stage residual inclusion (2 SRI ) GEE model, which further accounted for the unobserved confounding factors. The PIM prescription rate of the physician most frequently visited by each patient was used as the IV . Principal Findings The naive GEE models indicated that patient PIM use was associated with a higher likelihood of hospitalization (odds ratio [ OR ], 1.399; 95 percent confidence interval [ CI ], 1.363–1.435). Using the physician PIM prescribing rate as an IV , we identified a stronger significant association between PIM and hospitalization ( OR , 1.990; 95 percent CI , 1.647–2.403). Conclusions PIM use is associated with increased hospitalization in elderly individuals. Adjusting for unobserved confounders is needed to obtain unbiased estimates of the relationship between PIM and health care outcomes." @default.
• W2172952877 created "2016-06-24" @default.
• W2172952877 creator A5058960992 @default.
• W2172952877 creator A5089338867 @default.
• W2172952877 date "2015-11-25" @default.
• W2172952877 modified "2023-10-16" @default.
• W2172952877 title "Potentially Inappropriate Medication and Health Care Outcomes: An Instrumental Variable Approach" @default.
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• W2172952877 doi "https://doi.org/10.1111/1475-6773.12417" @default.
• W2172952877 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4946035" @default.
• W2172952877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26601656" @default.
• W2172952877 hasPublicationYear "2015" @default.
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