FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2172962518> ?p ?o ?g. }

• W2172962518 endingPage "838" @default.
• W2172962518 startingPage "825" @default.
• W2172962518 abstract "Phosphatidylethanol species (PEths) are promising biomarkers of alcohol consumption. Here, we report on the set-up, validation, and application of a novel UHPLC-ESI-MS/MS method for the quantification of PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 in whole blood (30 μL) and in venous (V, 30 μL) or capillary (C, 3 punches (3 mm)) dried blood spots (DBS). The methods were linear from 10 (LLOQ) to 2000 ng/mL for PEth 16:0/18:1, from 10 (LLOQ) to 1940 ng/mL for PEth 18:1/18:1, and from 19 (LLOQ) to 3872 ng/mL for PEth 16:0/16:0. Extraction efficiencies were higher than 55% (RSD < 18%) and matrix effects compensated for by IS were between 77 and 125% (RSD < 10%). Accuracy, repeatability, and intermediate precision fulfilled acceptance criteria (bias and RSD below 13%). Validity of the procedure for determination of PEth 16:0/18:1 in blood was demonstrated by the successful participation in a proficiency test. The quantification of PEths in C-DBS was not significantly influenced by the hematocrit, punch localization, or spot volume. The stability of PEths in V-DBS stored at room temperature was demonstrated up to 6 months. The method was applied to authentic samples (whole blood, V-DBS, and C-DBS) from 50 inpatients in alcohol withdrawal and 50 control volunteers. Applying a cut-off value to detect inpatients at 221 ng/mL for PEth 16:0/18:1 provided no false positive results and a good sensitivity (86%). Comparison of quantitative results (Bland-Altman plot, Passing-Bablok regression, and Wilcoxon signed rank test) revealed that V-DBS and C-DBS were valid alternatives to venous blood for the detection of alcohol consumption." @default.
• W2172962518 created "2016-06-24" @default.
• W2172962518 creator A5005262268 @default.
• W2172962518 creator A5006536172 @default.
• W2172962518 creator A5044766996 @default.
• W2172962518 creator A5067066181 @default.
• W2172962518 creator A5084552118 @default.
• W2172962518 creator A5086526223 @default.
• W2172962518 creator A5088392796 @default.
• W2172962518 creator A5089838749 @default.
• W2172962518 date "2015-11-23" @default.
• W2172962518 modified "2023-10-17" @default.
• W2172962518 title "Quantification of phosphatidylethanol 16:0/18:1, 18:1/18:1, and 16:0/16:0 in venous blood and venous and capillary dried blood spots from patients in alcohol withdrawal and control volunteers" @default.
• W2172962518 cites W1485401593 @default.
• W2172962518 cites W1972760580 @default.
• W2172962518 cites W1973979122 @default.
• W2172962518 cites W1977094916 @default.
• W2172962518 cites W1981898840 @default.
• W2172962518 cites W1999221499 @default.
• W2172962518 cites W1999957028 @default.
• W2172962518 cites W2002251346 @default.
• W2172962518 cites W2004694130 @default.
• W2172962518 cites W2014152172 @default.
• W2172962518 cites W2016773744 @default.
• W2172962518 cites W2018653716 @default.
• W2172962518 cites W2020689699 @default.
• W2172962518 cites W2029596059 @default.
• W2172962518 cites W2030976541 @default.
• W2172962518 cites W2032901572 @default.
• W2172962518 cites W2047497393 @default.
• W2172962518 cites W2047900500 @default.
• W2172962518 cites W2050226999 @default.
• W2172962518 cites W2060967796 @default.
• W2172962518 cites W2061579239 @default.
• W2172962518 cites W2068734383 @default.
• W2172962518 cites W2084543715 @default.
• W2172962518 cites W2085524913 @default.
• W2172962518 cites W2101218751 @default.
• W2172962518 cites W2116419819 @default.
• W2172962518 cites W2120542930 @default.
• W2172962518 cites W2122075984 @default.
• W2172962518 cites W2134319366 @default.
• W2172962518 cites W2141541868 @default.
• W2172962518 cites W2154769629 @default.
• W2172962518 cites W2172568906 @default.
• W2172962518 doi "https://doi.org/10.1007/s00216-015-9169-1" @default.
• W2172962518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26597914" @default.
• W2172962518 hasPublicationYear "2015" @default.
• W2172962518 type Work @default.
• W2172962518 sameAs 2172962518 @default.
• W2172962518 citedByCount "64" @default.
• W2172962518 countsByYear W21729625182016 @default.
• W2172962518 countsByYear W21729625182017 @default.
• W2172962518 countsByYear W21729625182018 @default.
• W2172962518 countsByYear W21729625182019 @default.
• W2172962518 countsByYear W21729625182020 @default.
• W2172962518 countsByYear W21729625182021 @default.
• W2172962518 countsByYear W21729625182022 @default.
• W2172962518 countsByYear W21729625182023 @default.
• W2172962518 crossrefType "journal-article" @default.
• W2172962518 hasAuthorship W2172962518A5005262268 @default.
• W2172962518 hasAuthorship W2172962518A5006536172 @default.
• W2172962518 hasAuthorship W2172962518A5044766996 @default.
• W2172962518 hasAuthorship W2172962518A5067066181 @default.
• W2172962518 hasAuthorship W2172962518A5084552118 @default.
• W2172962518 hasAuthorship W2172962518A5086526223 @default.
• W2172962518 hasAuthorship W2172962518A5088392796 @default.
• W2172962518 hasAuthorship W2172962518A5089838749 @default.
• W2172962518 hasBestOaLocation W21729625182 @default.
• W2172962518 hasConcept C126322002 @default.
• W2172962518 hasConcept C154020017 @default.
• W2172962518 hasConcept C1621761 @default.
• W2172962518 hasConcept C185592680 @default.
• W2172962518 hasConcept C2776330855 @default.
• W2172962518 hasConcept C2776597655 @default.
• W2172962518 hasConcept C2778918659 @default.
• W2172962518 hasConcept C2780202252 @default.
• W2172962518 hasConcept C2780959883 @default.
• W2172962518 hasConcept C2781066024 @default.
• W2172962518 hasConcept C3017516299 @default.
• W2172962518 hasConcept C41625074 @default.
• W2172962518 hasConcept C43044207 @default.
• W2172962518 hasConcept C43617362 @default.
• W2172962518 hasConcept C55493867 @default.
• W2172962518 hasConcept C71924100 @default.
• W2172962518 hasConceptScore W2172962518C126322002 @default.
• W2172962518 hasConceptScore W2172962518C154020017 @default.
• W2172962518 hasConceptScore W2172962518C1621761 @default.
• W2172962518 hasConceptScore W2172962518C185592680 @default.
• W2172962518 hasConceptScore W2172962518C2776330855 @default.
• W2172962518 hasConceptScore W2172962518C2776597655 @default.
• W2172962518 hasConceptScore W2172962518C2778918659 @default.
• W2172962518 hasConceptScore W2172962518C2780202252 @default.
• W2172962518 hasConceptScore W2172962518C2780959883 @default.
• W2172962518 hasConceptScore W2172962518C2781066024 @default.
• W2172962518 hasConceptScore W2172962518C3017516299 @default.
• W2172962518 hasConceptScore W2172962518C41625074 @default.
• W2172962518 hasConceptScore W2172962518C43044207 @default.

• next