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- W2173242512 abstract "Oral anticoagulation therapy is essential in patients with atrial fibrillation and clinicians need guidance on decision-making between the vitamin K antagonists (VKA), e.g. warfarin, or non-vitamin K antagonist oral anticoagulants. Observational studies have shown that patients who receive VKA therapy spend a significant percentage of their time with international normalized ratio values outside of the therapeutic range (time in therapeutic range, TTR <60%.) Recently, a clinical score has been developed with commonly encountered clinical features, the SAMe-TT2R2 score, to help decision-making with regard to whether a patient is likely to do well, or not, with a VKA. Those with a SAMe-TT2R2 score of 0–1 are likely to do well on a VKA, while those with a SAMe-TT2R2 score ≥2 are on probability going to achieve suboptimal TTR. In this article, we provide an overview of the main published retrospective and prospective studies that have validated the SAMe-TT2R2 score and its value for decision-making in daily clinical practice." @default.
- W2173242512 created "2016-06-24" @default.
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- W2173242512 date "2015-12-09" @default.
- W2173242512 modified "2023-09-24" @default.
- W2173242512 title "The SAMe-TT<sub>2</sub>R<sub>2</sub>score and decision-making between a vitamin K antagonist or a non-vitamin K antagonist oral anticoagulant in patients with atrial fibrillation" @default.
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- W2173242512 doi "https://doi.org/10.1586/14779072.2016.1116941" @default.
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