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- W2173840304 abstract "The preparation of 2,3,5-trisubstituted-furo[3,2-b]pyridines via a Pd(0)-catalyzed intramolecular cyclization of methyl 4-(6-chloro-2-iodopyridin-3-yloxy)-substituted-butenoates 9a–f is described. This approach was both efficient and general, and provided the highly functionalized heterocyclic ring system in high yield. Among the several examples provided is the preparation of 3-[2-(N,N-dimethylamino)ethyl]-5-(4-fluorobenzoyl)amino-2-methylfuro[3,2-b]pyridine 4, a selective 5-HT1F receptor agonist." @default.
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- W2173840304 date "2003-01-01" @default.
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- W2173840304 title "A general method for the preparation of 2,3,5-trisubstituted-furo[3,2-b]pyridines" @default.
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- W2173840304 doi "https://doi.org/10.1016/s0040-4039(02)02655-2" @default.
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