FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2173929482> ?p ?o ?g. }

• W2173929482 endingPage "14" @default.
• W2173929482 startingPage "1" @default.
• W2173929482 abstract "African Dust Events (ADE) are a seasonal phenomenon that has been suggested to exacerbate respiratory and proinflammatory diseases in Puerto Rico (PR). Increases in PM10 concentration and the effects of biological endotoxins (ENX) are critical factors to consider during these storms. ENX promote proinflammatory responses in lungs of susceptible individuals through activation of the Toll-like receptors (TLR2/4) signaling pathways. The objective of the study was to evaluate the toxicological and proinflammatory responses stimulated by ADE PM10 ENX reaching PR using human bronchial epithelial cells. PM10 organic extracts from a rural and urban site in PR (March 2004) were obtained from ADE and non-ADE and compared. A retrospective data analysis (PM10 concentration, aerosol images, and pediatric asthma claims) was performed from 2000 to 2012 with particular emphasis in 2004 to classify PM samples. Urban extracts were highly toxic, proinflammatory (IL-6/IL-8 secretion), and induced higher TLR4 expression and NF-κB activation compared to rural extracts. ENX were found to contribute to cytotoxicity and inflammatory responses provoked by urban ADE PM10 exposure suggesting a synergistic potency of local and natural ENX incoming from ADE. The contribution of ADE PM10 ENX is valuable in order to understand interactions and action mechanisms of airborne pollutants as asthma triggers in PR." @default.
• W2173929482 created "2016-06-24" @default.
• W2173929482 creator A5012627183 @default.
• W2173929482 creator A5040422535 @default.
• W2173929482 creator A5077846863 @default.
• W2173929482 creator A5083516752 @default.
• W2173929482 creator A5088987746 @default.
• W2173929482 date "2015-01-01" @default.
• W2173929482 modified "2023-10-18" @default.
• W2173929482 title "Linking Endotoxins, African Dust PM₁₀and Asthma in an Urban and Rural Environment of Puerto Rico" @default.
• W2173929482 cites W1523689878 @default.
• W2173929482 cites W1564841300 @default.
• W2173929482 cites W1593676412 @default.
• W2173929482 cites W1600500540 @default.
• W2173929482 cites W1964854788 @default.
• W2173929482 cites W1966365711 @default.
• W2173929482 cites W1967870152 @default.
• W2173929482 cites W1968414214 @default.
• W2173929482 cites W1969457486 @default.
• W2173929482 cites W1971614530 @default.
• W2173929482 cites W1973392715 @default.
• W2173929482 cites W1978653090 @default.
• W2173929482 cites W1979015109 @default.
• W2173929482 cites W1982657845 @default.
• W2173929482 cites W1984009390 @default.
• W2173929482 cites W1984993454 @default.
• W2173929482 cites W1985605588 @default.
• W2173929482 cites W1993619636 @default.
• W2173929482 cites W1995206728 @default.
• W2173929482 cites W1996959613 @default.
• W2173929482 cites W1997200490 @default.
• W2173929482 cites W1999963634 @default.
• W2173929482 cites W2002075318 @default.
• W2173929482 cites W2003544664 @default.
• W2173929482 cites W2009080406 @default.
• W2173929482 cites W2009363241 @default.
• W2173929482 cites W2011737595 @default.
• W2173929482 cites W2012221646 @default.
• W2173929482 cites W2014298752 @default.
• W2173929482 cites W2019681376 @default.
• W2173929482 cites W2023057212 @default.
• W2173929482 cites W2023746601 @default.
• W2173929482 cites W2026398980 @default.
• W2173929482 cites W2028866138 @default.
• W2173929482 cites W2030445630 @default.
• W2173929482 cites W2030960475 @default.
• W2173929482 cites W2036444132 @default.
• W2173929482 cites W2036967608 @default.
• W2173929482 cites W2038886322 @default.
• W2173929482 cites W2039044077 @default.
• W2173929482 cites W2039315626 @default.
• W2173929482 cites W2042170753 @default.
• W2173929482 cites W2050237494 @default.
• W2173929482 cites W2060746859 @default.
• W2173929482 cites W2065915947 @default.
• W2173929482 cites W2068009719 @default.
• W2173929482 cites W2072960495 @default.
• W2173929482 cites W2075211725 @default.
• W2173929482 cites W2076145115 @default.
• W2173929482 cites W2076932759 @default.
• W2173929482 cites W2083784656 @default.
• W2173929482 cites W2086489901 @default.
• W2173929482 cites W2087825633 @default.
• W2173929482 cites W2091426331 @default.
• W2173929482 cites W2094338605 @default.
• W2173929482 cites W2095126151 @default.
• W2173929482 cites W2096630086 @default.
• W2173929482 cites W2097473540 @default.
• W2173929482 cites W2098275471 @default.
• W2173929482 cites W2098576596 @default.
• W2173929482 cites W2101363646 @default.
• W2173929482 cites W2104786214 @default.
• W2173929482 cites W2117471479 @default.
• W2173929482 cites W2117723154 @default.
• W2173929482 cites W2123379708 @default.
• W2173929482 cites W2123998392 @default.
• W2173929482 cites W2128331422 @default.
• W2173929482 cites W2129853879 @default.
• W2173929482 cites W2136301923 @default.
• W2173929482 cites W2143127434 @default.
• W2173929482 cites W2149311494 @default.
• W2173929482 cites W2150553281 @default.
• W2173929482 cites W2155774292 @default.
• W2173929482 cites W2161852451 @default.
• W2173929482 cites W2161928149 @default.
• W2173929482 cites W2166431583 @default.
• W2173929482 cites W2169111245 @default.
• W2173929482 cites W2188282397 @default.
• W2173929482 cites W747600451 @default.
• W2173929482 cites W775427028 @default.
• W2173929482 doi "https://doi.org/10.1155/2015/784212" @default.
• W2173929482 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4670654" @default.
• W2173929482 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26681839" @default.
• W2173929482 hasPublicationYear "2015" @default.
• W2173929482 type Work @default.
• W2173929482 sameAs 2173929482 @default.
• W2173929482 citedByCount "27" @default.
• W2173929482 countsByYear W21739294822016 @default.

• next