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- W2174206883 abstract "The bone contains the bone marrow. The functional communication between bone cells and hematopoiesis has been extensively studied in the past decade or so. Osteolineage cells and their modulators, such as the sympathetic nervous system, macrophages and osteoclasts, form a complex unit to maintain the homeostasis of hematopoiesis, called the 'microenvironment'. Recently, bone-embedded osteocytes, the sensors of gravity and mechanical stress, have joined the microenvironment, and they are demonstrated to contribute to whole body homeostasis through the control of immunity and energy metabolism. The inter-organ communication orchestrated by the bone is summarized in this article." @default.
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- W2174206883 date "2015-10-07" @default.
- W2174206883 modified "2023-10-16" @default.
- W2174206883 title "Communication of bone cells with hematopoiesis, immunity and energy metabolism" @default.
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- W2174206883 doi "https://doi.org/10.1038/bonekey.2015.117" @default.
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