FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2174752725> ?p ?o ?g. }

• W2174752725 endingPage "221" @default.
• W2174752725 startingPage "209" @default.
• W2174752725 abstract "The Canadian Immunohistochemistry Quality Control provides proficiency testing for immunohistochemistry in Canadian laboratories. Canadian Immunohistochemistry Quality Control Run 42 assessed WT1, Napsin A, and p53; commonly used markers for histotyping ovarian carcinomas. A 42-core tissue microarray, which included the 5 major histotypes of ovarian carcinomas with a subset having known TP53 mutational status, was used for this Canadian Immunohistochemistry Quality Control challenge. Participants included 43 laboratories for p53, 29 for WT1, and 26 for Napsin A. p53 was scored as aberrant if the staining was strong and diffuse or absent. Napsin A and WT1 were scored positive if any tumor cells stained. The reference p53 expression pattern was inferred by TP53 mutation type when available. For WT1, Napsin A, and cases lacking mutational data, the reference staining pattern was based on the majority staining result. The error rate for p53 was 8.8%. Most errors (84%) were due to weak staining. The sensitivity and specificity of aberrant p53 expression for an underlying TP53 mutation was 91.6% and 87.9%, respectively. The error rate for WT1 was 0.76% with all errors occurring in laboratories using the 6F-h2 clone. The average errors for laboratories using 6F-h2 were 2.4 compared with 0 for WT-49. The error rate for Napsin A was 4%. The average errors for laboratories using polyclonal Napsin A were 3 compared with 1.1 for monoclonal Napsin A. Weak p53 staining increases interpretative errors, primarily due to absence of staining in tumors with wild-type TP53. p53 immunohistochemistry correlates strongly with TP53 mutational status. Polyclonal Napsin A and 6F-h2 may lack specificity in comparison to monoclonal Napsin A and WT-49." @default.
• W2174752725 created "2016-06-24" @default.
• W2174752725 creator A5009546869 @default.
• W2174752725 creator A5020493456 @default.
• W2174752725 creator A5046749955 @default.
• W2174752725 creator A5052794976 @default.
• W2174752725 creator A5058317335 @default.
• W2174752725 creator A5065014768 @default.
• W2174752725 creator A5070217428 @default.
• W2174752725 creator A5074182063 @default.
• W2174752725 creator A5085086748 @default.
• W2174752725 creator A5086449500 @default.
• W2174752725 date "2016-05-01" @default.
• W2174752725 modified "2023-10-16" @default.
• W2174752725 title "Calibration and Optimization of p53, WT1, and Napsin A Immunohistochemistry Ancillary Tests for Histotyping of Ovarian Carcinoma" @default.
• W2174752725 cites W1578826342 @default.
• W2174752725 cites W1587415694 @default.
• W2174752725 cites W1965456845 @default.
• W2174752725 cites W1967975273 @default.
• W2174752725 cites W1968362667 @default.
• W2174752725 cites W1971083266 @default.
• W2174752725 cites W1972182149 @default.
• W2174752725 cites W1991356855 @default.
• W2174752725 cites W2002604331 @default.
• W2174752725 cites W2002817208 @default.
• W2174752725 cites W2009205448 @default.
• W2174752725 cites W2011581825 @default.
• W2174752725 cites W2017408894 @default.
• W2174752725 cites W2030922808 @default.
• W2174752725 cites W2033737920 @default.
• W2174752725 cites W2034455009 @default.
• W2174752725 cites W2038334562 @default.
• W2174752725 cites W2038603141 @default.
• W2174752725 cites W2050511691 @default.
• W2174752725 cites W2066108428 @default.
• W2174752725 cites W2072455059 @default.
• W2174752725 cites W2084148547 @default.
• W2174752725 cites W2090853702 @default.
• W2174752725 cites W2091017768 @default.
• W2174752725 cites W2112712780 @default.
• W2174752725 cites W2113415002 @default.
• W2174752725 cites W2118228232 @default.
• W2174752725 cites W2129355295 @default.
• W2174752725 cites W2138588225 @default.
• W2174752725 cites W2139288543 @default.
• W2174752725 cites W2141245433 @default.
• W2174752725 cites W2149541861 @default.
• W2174752725 cites W2161701941 @default.
• W2174752725 cites W2162832987 @default.
• W2174752725 cites W2168808424 @default.
• W2174752725 cites W2314787270 @default.
• W2174752725 cites W2321628205 @default.
• W2174752725 cites W4229854891 @default.
• W2174752725 doi "https://doi.org/10.1097/pgp.0000000000000251" @default.
• W2174752725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26598982" @default.
• W2174752725 hasPublicationYear "2016" @default.
• W2174752725 type Work @default.
• W2174752725 sameAs 2174752725 @default.
• W2174752725 citedByCount "28" @default.
• W2174752725 countsByYear W21747527252016 @default.
• W2174752725 countsByYear W21747527252017 @default.
• W2174752725 countsByYear W21747527252018 @default.
• W2174752725 countsByYear W21747527252019 @default.
• W2174752725 countsByYear W21747527252020 @default.
• W2174752725 countsByYear W21747527252021 @default.
• W2174752725 countsByYear W21747527252022 @default.
• W2174752725 countsByYear W21747527252023 @default.
• W2174752725 crossrefType "journal-article" @default.
• W2174752725 hasAuthorship W2174752725A5009546869 @default.
• W2174752725 hasAuthorship W2174752725A5020493456 @default.
• W2174752725 hasAuthorship W2174752725A5046749955 @default.
• W2174752725 hasAuthorship W2174752725A5052794976 @default.
• W2174752725 hasAuthorship W2174752725A5058317335 @default.
• W2174752725 hasAuthorship W2174752725A5065014768 @default.
• W2174752725 hasAuthorship W2174752725A5070217428 @default.
• W2174752725 hasAuthorship W2174752725A5074182063 @default.
• W2174752725 hasAuthorship W2174752725A5085086748 @default.
• W2174752725 hasAuthorship W2174752725A5086449500 @default.
• W2174752725 hasConcept C104317684 @default.
• W2174752725 hasConcept C121608353 @default.
• W2174752725 hasConcept C126322002 @default.
• W2174752725 hasConcept C142724271 @default.
• W2174752725 hasConcept C193270364 @default.
• W2174752725 hasConcept C204232928 @default.
• W2174752725 hasConcept C2777546739 @default.
• W2174752725 hasConcept C2780427987 @default.
• W2174752725 hasConcept C2908651487 @default.
• W2174752725 hasConcept C3019054536 @default.
• W2174752725 hasConcept C54355233 @default.
• W2174752725 hasConcept C71924100 @default.
• W2174752725 hasConcept C74864618 @default.
• W2174752725 hasConcept C81089528 @default.
• W2174752725 hasConcept C86803240 @default.
• W2174752725 hasConceptScore W2174752725C104317684 @default.
• W2174752725 hasConceptScore W2174752725C121608353 @default.
• W2174752725 hasConceptScore W2174752725C126322002 @default.
• W2174752725 hasConceptScore W2174752725C142724271 @default.
• W2174752725 hasConceptScore W2174752725C193270364 @default.

• next