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- W2175164429 abstract "A small interfering double stranded RNA molecule (siRNA, 21 bp) corresponding to a portion (nucleotides 337 to 357) of domain 3 of the human dUTPase was synthesized and used to determine whether it could down-regulate dUTPase activity in human cells. Transfection of the siRNA into HeLa and HT29 cells resulted in a 56 +/- 3.6% decrease in dUTPase activity, while transfection of SW620 cells resulted in a 27 +/- 6% decrease in dUTPase activity when compared to non-treated controls." @default.
- W2175164429 created "2016-06-24" @default.
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- W2175164429 date "2004-12-31" @default.
- W2175164429 modified "2023-10-17" @default.
- W2175164429 title "Down–Regulation of Human Deoxyuridine Triphosphate Nucleotidohydrolase (dUTPase) Using Small Interfering RNA (siRNA)" @default.
- W2175164429 cites W1985806933 @default.
- W2175164429 cites W2013822978 @default.
- W2175164429 doi "https://doi.org/10.1081/ncn-200027684" @default.
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