FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2175280609> ?p ?o ?g. }

• W2175280609 endingPage "385" @default.
• W2175280609 startingPage "380" @default.
• W2175280609 abstract "Commercial Marek's disease (MD) vaccines produced by two manufacturers were tested for possible contamination with avian leukosis virus (ALV). Samples of MD vaccines manufactured by two companies (A and B) were received from a breeder company; samples were also received directly from vaccine company B. Using virus isolation tests, samples initially tested positive for subgroup E (endogenous) ALV. However, upon repassage, the vaccines also tested positive for exogenous ALV. The isolated exogenous ALV proved to be a subgroup A virus, as determined by flow cytometry using polyclonal chicken antibodies specific for various subgroups of ALV, and by DNA sequencing of the envelope glygoprotein (gp85). The exogenous ALV isolated from MD vaccines was inoculated in chickens from ADOL lines 15I5 × 71 and 0 to determine its pathogenicity and compare it with that of Rous-associated-virus–1 (RAV-1), the prototype strain of ALV-A. Each chicken from each line was inoculated with approximately 10,000 infectious units of RAV-1 or the ALV-A isolated from vaccines termed B-39 virus at 7th day of embryonation. At hatch, and at 4, 8, and 16 wk of age, chickens were tested for viremia and cloacal shedding; chickens were also observed for ALV-induced tumors within 16 wk of age. Viremia and cloacal shedding results suggest that chickens from both lines were susceptible to infection with either virus. Within 16 wk of age, the proportion of ALV tumors induced by strain B-39 in line 0 and line 15I5 × 71 chickens was 0% and 12%, respectively, compared with 62% and 67% in chickens inoculated with RAV-1. The data indicate that commercial MD vaccines produced by two manufacturers were contaminated with endogenous subgroup E and an exogenous subgroup A ALV. Further, data from biological characterization suggest that the ALV-A isolated from commercial MD vaccines is of low oncogenicity, compared with that of RAV-1.GenBank accession numbers: The gp85 gene sequences of ALV isolated from commercial Marek's disease vaccines have been deposited in GenBank and assigned the following accession numbers: A46 subgroup A, DQ412726 ; B53 subgroup A, DQ412727; A46 subgroup E, DQ412728; B53 subgroup E, DQ412729." @default.
• W2175280609 created "2016-06-24" @default.
• W2175280609 creator A5002822533 @default.
• W2175280609 creator A5033234402 @default.
• W2175280609 creator A5044277301 @default.
• W2175280609 creator A5072782581 @default.
• W2175280609 creator A5075442487 @default.
• W2175280609 date "2006-09-01" @default.
• W2175280609 modified "2023-09-27" @default.
• W2175280609 title "Isolation and Characterization of an Adventitious Avian Leukosis Virus Isolated from Commercial Marek's Disease Vaccines" @default.
• W2175280609 cites W1621100684 @default.
• W2175280609 cites W1965332354 @default.
• W2175280609 cites W2032151588 @default.
• W2175280609 cites W2046260534 @default.
• W2175280609 cites W2060478481 @default.
• W2175280609 cites W2066463223 @default.
• W2175280609 cites W2075710582 @default.
• W2175280609 cites W2091215453 @default.
• W2175280609 cites W2097940436 @default.
• W2175280609 cites W2164783203 @default.
• W2175280609 cites W2164920364 @default.
• W2175280609 cites W2321067211 @default.
• W2175280609 cites W2329017497 @default.
• W2175280609 cites W2331502478 @default.
• W2175280609 doi "https://doi.org/10.1637/7497-122905r.1" @default.
• W2175280609 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17039837" @default.
• W2175280609 hasPublicationYear "2006" @default.
• W2175280609 type Work @default.
• W2175280609 sameAs 2175280609 @default.
• W2175280609 citedByCount "32" @default.
• W2175280609 countsByYear W21752806092012 @default.
• W2175280609 countsByYear W21752806092013 @default.
• W2175280609 countsByYear W21752806092014 @default.
• W2175280609 countsByYear W21752806092015 @default.
• W2175280609 countsByYear W21752806092016 @default.
• W2175280609 countsByYear W21752806092017 @default.
• W2175280609 countsByYear W21752806092018 @default.
• W2175280609 countsByYear W21752806092019 @default.
• W2175280609 countsByYear W21752806092021 @default.
• W2175280609 crossrefType "journal-article" @default.
• W2175280609 hasAuthorship W2175280609A5002822533 @default.
• W2175280609 hasAuthorship W2175280609A5033234402 @default.
• W2175280609 hasAuthorship W2175280609A5044277301 @default.
• W2175280609 hasAuthorship W2175280609A5072782581 @default.
• W2175280609 hasAuthorship W2175280609A5075442487 @default.
• W2175280609 hasConcept C12914427 @default.
• W2175280609 hasConcept C134215735 @default.
• W2175280609 hasConcept C151730666 @default.
• W2175280609 hasConcept C159047783 @default.
• W2175280609 hasConcept C159654299 @default.
• W2175280609 hasConcept C180032290 @default.
• W2175280609 hasConcept C203014093 @default.
• W2175280609 hasConcept C2522874641 @default.
• W2175280609 hasConcept C2776185481 @default.
• W2175280609 hasConcept C2777852405 @default.
• W2175280609 hasConcept C2909249321 @default.
• W2175280609 hasConcept C86803240 @default.
• W2175280609 hasConceptScore W2175280609C12914427 @default.
• W2175280609 hasConceptScore W2175280609C134215735 @default.
• W2175280609 hasConceptScore W2175280609C151730666 @default.
• W2175280609 hasConceptScore W2175280609C159047783 @default.
• W2175280609 hasConceptScore W2175280609C159654299 @default.
• W2175280609 hasConceptScore W2175280609C180032290 @default.
• W2175280609 hasConceptScore W2175280609C203014093 @default.
• W2175280609 hasConceptScore W2175280609C2522874641 @default.
• W2175280609 hasConceptScore W2175280609C2776185481 @default.
• W2175280609 hasConceptScore W2175280609C2777852405 @default.
• W2175280609 hasConceptScore W2175280609C2909249321 @default.
• W2175280609 hasConceptScore W2175280609C86803240 @default.
• W2175280609 hasIssue "3" @default.
• W2175280609 hasLocation W21752806091 @default.
• W2175280609 hasLocation W21752806092 @default.
• W2175280609 hasOpenAccess W2175280609 @default.
• W2175280609 hasPrimaryLocation W21752806091 @default.
• W2175280609 hasRelatedWork W1987592857 @default.
• W2175280609 hasRelatedWork W2036754569 @default.
• W2175280609 hasRelatedWork W2082080978 @default.
• W2175280609 hasRelatedWork W2094603343 @default.
• W2175280609 hasRelatedWork W2150845218 @default.
• W2175280609 hasRelatedWork W2166925281 @default.
• W2175280609 hasRelatedWork W2167948064 @default.
• W2175280609 hasRelatedWork W2225970454 @default.
• W2175280609 hasRelatedWork W2321703299 @default.
• W2175280609 hasRelatedWork W74685249 @default.
• W2175280609 hasVolume "50" @default.
• W2175280609 isParatext "false" @default.
• W2175280609 isRetracted "false" @default.
• W2175280609 magId "2175280609" @default.
• W2175280609 workType "article" @default.