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- W2175459053 abstract "Summary A method is described of performing acute total gastric pouch secretory studies in anesthetized cats. The maximal secretory capacity of the gastric epithelium in these preparations was influenced by the duration of histamine administration as well as the dose. It is possible to obtain a larger output of gastric juice for a short period by doubling the dose of histamine each 2 hours than by giving a larger dose over a prolonged test. The correlations between the ionic concentrations in the stimulated and in the unstimulated cats are on the whole consistent with Hollander's two-component theory of gastric secretion. The composition of the two components differs in the two states, the chief difference being an increase in the K concentration in the nonparietal cell secretion on stimulation, with a corresponding decrease in the K in the parietal cell secretion. Histamine increases the rates of both secretions with a greater increase in the parietal cell secretion. The reason for the K content of parietal secretion, which is at variance with the Hollander theory, is not clear but may be due to species difference, to retained innervation of the stomach or to the anesthetic." @default.
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- W2175459053 date "1963-05-01" @default.
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- W2175459053 title "Histamine Secretory Tests in Cats: An Evaluation of Results Based Upon Hollander's Two-Component Theory" @default.
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- W2175459053 doi "https://doi.org/10.1016/s0016-5085(63)80038-4" @default.
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