Matches in SemOpenAlex for { <https://semopenalex.org/work/W2175580086> ?p ?o ?g. }
- W2175580086 endingPage "33" @default.
- W2175580086 startingPage "15" @default.
- W2175580086 abstract "Wall shear stress (WSS) is a very important hemodynamic parameter implicated in many physiological and pathological phenomena. In order to study these phenomena, it is more convenient to use in vitro models before testing on animals and humans. Dynamic in vitro cerebrovascular models are considered capable of simulating the in vivo hemodynamic conditions, but only few of them seem to meet the criteria for this task. It is now clear that in the human eye microcirculation a significant pulsation exists at the pre-capillary arterioles with average WSS values more than twice those in the venular side, for the same diameters. WSS heterogeneity is in support of segmental heterogeneity i.e. the endothelial phenotypic and functional difference among arterioles, capillaries and venules. In this review paper, the importance of WSS is described in detail and two more microvascular segments are proposed: a pre-capillary arteriolar and a post-capillary venular segment. The accurate hemodynamic simulation in all microvascular segments seems to be a prerequisite step in the development of dynamic in vitro blood brain barrier (BBB) models and microfluidic platforms on chip. Endothelial cells in the cardiovascular system seem to have sophisticated role acting like cardiovascular processing sensors (CPSs)." @default.
- W2175580086 created "2016-06-24" @default.
- W2175580086 creator A5003154730 @default.
- W2175580086 date "2016-07-01" @default.
- W2175580086 modified "2023-09-25" @default.
- W2175580086 title "Wall shear stress in the human eye microcirculation in vivo, segmental heterogeneity and performance of in vitro cerebrovascular models" @default.
- W2175580086 cites W1564350877 @default.
- W2175580086 cites W1567244432 @default.
- W2175580086 cites W1625041379 @default.
- W2175580086 cites W1635868832 @default.
- W2175580086 cites W17754298 @default.
- W2175580086 cites W1795220919 @default.
- W2175580086 cites W1834747511 @default.
- W2175580086 cites W1928562519 @default.
- W2175580086 cites W1963898851 @default.
- W2175580086 cites W1965526093 @default.
- W2175580086 cites W1965838612 @default.
- W2175580086 cites W1966471880 @default.
- W2175580086 cites W1968150858 @default.
- W2175580086 cites W1974869899 @default.
- W2175580086 cites W1975348834 @default.
- W2175580086 cites W197598219 @default.
- W2175580086 cites W1976439848 @default.
- W2175580086 cites W1981175423 @default.
- W2175580086 cites W1982748428 @default.
- W2175580086 cites W1983177758 @default.
- W2175580086 cites W1984204348 @default.
- W2175580086 cites W1985653417 @default.
- W2175580086 cites W1989012631 @default.
- W2175580086 cites W1989939869 @default.
- W2175580086 cites W1992718978 @default.
- W2175580086 cites W1994504773 @default.
- W2175580086 cites W1994812037 @default.
- W2175580086 cites W1996001348 @default.
- W2175580086 cites W1996378347 @default.
- W2175580086 cites W1999083451 @default.
- W2175580086 cites W2000845808 @default.
- W2175580086 cites W2001091692 @default.
- W2175580086 cites W2001132215 @default.
- W2175580086 cites W2003607068 @default.
- W2175580086 cites W2007737411 @default.
- W2175580086 cites W2009851254 @default.
- W2175580086 cites W2010874323 @default.
- W2175580086 cites W2018317204 @default.
- W2175580086 cites W2019927236 @default.
- W2175580086 cites W2020331803 @default.
- W2175580086 cites W2021576512 @default.
- W2175580086 cites W2022863065 @default.
- W2175580086 cites W2024170393 @default.
- W2175580086 cites W2027096883 @default.
- W2175580086 cites W2028607959 @default.
- W2175580086 cites W2029541365 @default.
- W2175580086 cites W2029610231 @default.
- W2175580086 cites W2030928201 @default.
- W2175580086 cites W2032115883 @default.
- W2175580086 cites W2035489545 @default.
- W2175580086 cites W2040536713 @default.
- W2175580086 cites W2046832348 @default.
- W2175580086 cites W2047136147 @default.
- W2175580086 cites W2050935277 @default.
- W2175580086 cites W2052424841 @default.
- W2175580086 cites W2052766715 @default.
- W2175580086 cites W2054312358 @default.
- W2175580086 cites W2063145866 @default.
- W2175580086 cites W2065583215 @default.
- W2175580086 cites W2066445391 @default.
- W2175580086 cites W2068337543 @default.
- W2175580086 cites W2079100427 @default.
- W2175580086 cites W2081135553 @default.
- W2175580086 cites W2082356514 @default.
- W2175580086 cites W2085754209 @default.
- W2175580086 cites W2086145217 @default.
- W2175580086 cites W2087020733 @default.
- W2175580086 cites W2091574626 @default.
- W2175580086 cites W2091680093 @default.
- W2175580086 cites W2092171957 @default.
- W2175580086 cites W2100124039 @default.
- W2175580086 cites W2107527993 @default.
- W2175580086 cites W2109486328 @default.
- W2175580086 cites W2112809275 @default.
- W2175580086 cites W2114208677 @default.
- W2175580086 cites W2115598904 @default.
- W2175580086 cites W2115837828 @default.
- W2175580086 cites W2116759862 @default.
- W2175580086 cites W2122664147 @default.
- W2175580086 cites W2124957201 @default.
- W2175580086 cites W2126410943 @default.
- W2175580086 cites W2130870274 @default.
- W2175580086 cites W2133951367 @default.
- W2175580086 cites W2135425711 @default.
- W2175580086 cites W2137042148 @default.
- W2175580086 cites W2137186141 @default.
- W2175580086 cites W2149672347 @default.
- W2175580086 cites W2150782716 @default.
- W2175580086 cites W2152343301 @default.
- W2175580086 cites W2153161317 @default.
- W2175580086 cites W2157056295 @default.
- W2175580086 cites W2159161252 @default.