FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2175673889> ?p ?o ?g. }

• W2175673889 endingPage "95" @default.
• W2175673889 startingPage "84" @default.
• W2175673889 abstract "Glatiramer acetate (Copaxone®; GA) is a non-biological complex drug for multiple sclerosis. GA modulated thousands of genes in genome-wide expression studies conducted in THP-1 cells and mouse splenocytes. Comparing GA with differently-manufactured glatiramoid Polimunol (Synthon) in mice yielded hundreds of differentially expressed probesets, including biologically-relevant genes (e.g. Il18, adj p < 9e−6) and pathways. In human monocytes, 700+ probesets differed between Polimunol and GA, enriching for 130+ pathways including response to lipopolysaccharide (adj. p < 0.006). Key differences were confirmed by qRT-PCR (splenocytes) or proteomics (THP-1). These studies demonstrate the complexity of GA's mechanisms of action, and may help inform therapeutic equivalence assessment." @default.
• W2175673889 created "2016-06-24" @default.
• W2175673889 creator A5023113485 @default.
• W2175673889 creator A5023740657 @default.
• W2175673889 creator A5027408932 @default.
• W2175673889 creator A5033071953 @default.
• W2175673889 creator A5039849303 @default.
• W2175673889 creator A5041805882 @default.
• W2175673889 creator A5047722409 @default.
• W2175673889 creator A5057333614 @default.
• W2175673889 creator A5059021503 @default.
• W2175673889 creator A5060555624 @default.
• W2175673889 creator A5060935364 @default.
• W2175673889 creator A5070287844 @default.
• W2175673889 creator A5072461998 @default.
• W2175673889 creator A5072895924 @default.
• W2175673889 creator A5073369876 @default.
• W2175673889 creator A5075956430 @default.
• W2175673889 date "2016-01-01" @default.
• W2175673889 modified "2023-10-01" @default.
• W2175673889 title "Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition" @default.
• W2175673889 cites W1504018030 @default.
• W2175673889 cites W1963501039 @default.
• W2175673889 cites W1967496127 @default.
• W2175673889 cites W1975352555 @default.
• W2175673889 cites W1976444166 @default.
• W2175673889 cites W1981116369 @default.
• W2175673889 cites W1989151603 @default.
• W2175673889 cites W2002967638 @default.
• W2175673889 cites W2009873598 @default.
• W2175673889 cites W2018028549 @default.
• W2175673889 cites W2020173029 @default.
• W2175673889 cites W2021435584 @default.
• W2175673889 cites W2066629315 @default.
• W2175673889 cites W2087244141 @default.
• W2175673889 cites W2107665951 @default.
• W2175673889 cites W2133465414 @default.
• W2175673889 cites W2145212228 @default.
• W2175673889 cites W2156642970 @default.
• W2175673889 cites W2171907184 @default.
• W2175673889 cites W2172273303 @default.
• W2175673889 cites W380092721 @default.
• W2175673889 cites W4211010877 @default.
• W2175673889 cites W4247984479 @default.
• W2175673889 doi "https://doi.org/10.1016/j.jneuroim.2015.11.020" @default.
• W2175673889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26711576" @default.
• W2175673889 hasPublicationYear "2016" @default.
• W2175673889 type Work @default.
• W2175673889 sameAs 2175673889 @default.
• W2175673889 citedByCount "20" @default.
• W2175673889 countsByYear W21756738892016 @default.
• W2175673889 countsByYear W21756738892017 @default.
• W2175673889 countsByYear W21756738892018 @default.
• W2175673889 countsByYear W21756738892019 @default.
• W2175673889 countsByYear W21756738892021 @default.
• W2175673889 countsByYear W21756738892022 @default.
• W2175673889 countsByYear W21756738892023 @default.
• W2175673889 crossrefType "journal-article" @default.
• W2175673889 hasAuthorship W2175673889A5023113485 @default.
• W2175673889 hasAuthorship W2175673889A5023740657 @default.
• W2175673889 hasAuthorship W2175673889A5027408932 @default.
• W2175673889 hasAuthorship W2175673889A5033071953 @default.
• W2175673889 hasAuthorship W2175673889A5039849303 @default.
• W2175673889 hasAuthorship W2175673889A5041805882 @default.
• W2175673889 hasAuthorship W2175673889A5047722409 @default.
• W2175673889 hasAuthorship W2175673889A5057333614 @default.
• W2175673889 hasAuthorship W2175673889A5059021503 @default.
• W2175673889 hasAuthorship W2175673889A5060555624 @default.
• W2175673889 hasAuthorship W2175673889A5060935364 @default.
• W2175673889 hasAuthorship W2175673889A5070287844 @default.
• W2175673889 hasAuthorship W2175673889A5072461998 @default.
• W2175673889 hasAuthorship W2175673889A5072895924 @default.
• W2175673889 hasAuthorship W2175673889A5073369876 @default.
• W2175673889 hasAuthorship W2175673889A5075956430 @default.
• W2175673889 hasBestOaLocation W21756738891 @default.
• W2175673889 hasConcept C104317684 @default.
• W2175673889 hasConcept C147483822 @default.
• W2175673889 hasConcept C185592680 @default.
• W2175673889 hasConcept C189976730 @default.
• W2175673889 hasConcept C203014093 @default.
• W2175673889 hasConcept C2778577042 @default.
• W2175673889 hasConcept C2778754761 @default.
• W2175673889 hasConcept C2780640218 @default.
• W2175673889 hasConcept C46111723 @default.
• W2175673889 hasConcept C54355233 @default.
• W2175673889 hasConcept C70721500 @default.
• W2175673889 hasConcept C86803240 @default.
• W2175673889 hasConceptScore W2175673889C104317684 @default.
• W2175673889 hasConceptScore W2175673889C147483822 @default.
• W2175673889 hasConceptScore W2175673889C185592680 @default.
• W2175673889 hasConceptScore W2175673889C189976730 @default.
• W2175673889 hasConceptScore W2175673889C203014093 @default.
• W2175673889 hasConceptScore W2175673889C2778577042 @default.
• W2175673889 hasConceptScore W2175673889C2778754761 @default.
• W2175673889 hasConceptScore W2175673889C2780640218 @default.
• W2175673889 hasConceptScore W2175673889C46111723 @default.
• W2175673889 hasConceptScore W2175673889C54355233 @default.
• W2175673889 hasConceptScore W2175673889C70721500 @default.

• next