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- W2176419992 abstract "Ameloblastic carcinoma is a rare malignant epithelial odontogenic tumor that combines the histological features of ameloblastoma and cytological atypia, irrespective of the presence or absence of metastasis. A 36-year-old female presented with a 4-month history of a painful, ulcerated swelling in the posterior left mandible. Radiographic examination showed a unilocular radiolucency with cortical bone rupture. The preliminary diagnosis of ameloblastoma prompted an incisional biopsy. Histopathological examination revealed islands and cords of odontogenic epithelium with peripheral palisading columnar cells exhibiting reverse nuclear polarization. Stellate reticulum-like tissue was present in the center of the islands. In their vicinity, islands of cells with pleomorphism, hyperchromatism, nuclear atypia, focal necrosis, and frequent mitotic figures were identified. Immunohistochemical analysis revealed positivity for alpha-smooth muscle actin within the epithelial islands. The definitive diagnosis was ameloblastic carcinoma. The patient was referred to a head and neck surgical service." @default.
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- W2176419992 date "2015-08-01" @default.
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- W2176419992 title "Ameloblastic Carcinoma of the Mandible: A Case Report" @default.
- W2176419992 doi "https://doi.org/10.1016/j.oooo.2015.02.172" @default.
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