Matches in SemOpenAlex for { <https://semopenalex.org/work/W217653802> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W217653802 endingPage "222" @default.
- W217653802 startingPage "219" @default.
- W217653802 abstract "Chengqi mixture (CM) is a Chinese herbal mixture valuable in treating acute peritonitis. The anti-inflammatory action of Chengqi mixture was investigated on the synthesis of leukotriene B4 (LTB4) and 5-hydroxyeicosatetraenoic acid (5-HETE) of peritoneal macrophages in rats. These mediators were determined by Reverse Phase-High Performance Liquid Chromatography. The ultraviolet absorbance of LTB4 was 280 nm, and of 5-HETE was 235 nm. The results indicated different concentrations of CM significantly inhibited the synthesis of LTB4 compared with the control (P<0.01, n=16) and were dose dependent from 0.15 to 10 g/L. The inhibitory rate of CM for the LTB4 exceeded 95% and for 5-HETE was about 70% at the dose of 5 g/L. The inhibitory rate of CM was equal to that of the flufenamic acid group in which the final concentration was at 10−4M. The half inhibitory rates (IC50) of CM for LTB4 and that for 5-HETE were 0.8 g/L and 1.1 g/L respectively. It is suggested that the anti-inflammatory actions of CM was related to the inhibition of synthesis of LTB4 and 5-HETE from arachidonic acid via 5-lipoxygenase in macrophages." @default.
- W217653802 created "2016-06-24" @default.
- W217653802 creator A5027742147 @default.
- W217653802 creator A5034677944 @default.
- W217653802 creator A5052776807 @default.
- W217653802 creator A5053815965 @default.
- W217653802 creator A5056003555 @default.
- W217653802 date "1995-09-01" @default.
- W217653802 modified "2023-09-25" @default.
- W217653802 title "Effect of Chengqi(承气) mixture on the synthesis of LTB4 and 5-HETE of peritoneal macrophages in rats" @default.
- W217653802 cites W1511945572 @default.
- W217653802 cites W2004351423 @default.
- W217653802 cites W2142002787 @default.
- W217653802 doi "https://doi.org/10.1007/bf02942940" @default.
- W217653802 hasPublicationYear "1995" @default.
- W217653802 type Work @default.
- W217653802 sameAs 217653802 @default.
- W217653802 citedByCount "0" @default.
- W217653802 crossrefType "journal-article" @default.
- W217653802 hasAuthorship W217653802A5027742147 @default.
- W217653802 hasAuthorship W217653802A5034677944 @default.
- W217653802 hasAuthorship W217653802A5052776807 @default.
- W217653802 hasAuthorship W217653802A5053815965 @default.
- W217653802 hasAuthorship W217653802A5056003555 @default.
- W217653802 hasBestOaLocation W2176538021 @default.
- W217653802 hasConcept C126322002 @default.
- W217653802 hasConcept C181199279 @default.
- W217653802 hasConcept C185592680 @default.
- W217653802 hasConcept C2776685179 @default.
- W217653802 hasConcept C2776914184 @default.
- W217653802 hasConcept C2778078955 @default.
- W217653802 hasConcept C2779630222 @default.
- W217653802 hasConcept C43617362 @default.
- W217653802 hasConcept C55493867 @default.
- W217653802 hasConcept C71924100 @default.
- W217653802 hasConcept C90342290 @default.
- W217653802 hasConcept C98015330 @default.
- W217653802 hasConcept C98274493 @default.
- W217653802 hasConceptScore W217653802C126322002 @default.
- W217653802 hasConceptScore W217653802C181199279 @default.
- W217653802 hasConceptScore W217653802C185592680 @default.
- W217653802 hasConceptScore W217653802C2776685179 @default.
- W217653802 hasConceptScore W217653802C2776914184 @default.
- W217653802 hasConceptScore W217653802C2778078955 @default.
- W217653802 hasConceptScore W217653802C2779630222 @default.
- W217653802 hasConceptScore W217653802C43617362 @default.
- W217653802 hasConceptScore W217653802C55493867 @default.
- W217653802 hasConceptScore W217653802C71924100 @default.
- W217653802 hasConceptScore W217653802C90342290 @default.
- W217653802 hasConceptScore W217653802C98015330 @default.
- W217653802 hasConceptScore W217653802C98274493 @default.
- W217653802 hasIssue "3" @default.
- W217653802 hasLocation W2176538021 @default.
- W217653802 hasOpenAccess W217653802 @default.
- W217653802 hasPrimaryLocation W2176538021 @default.
- W217653802 hasRelatedWork W123069601 @default.
- W217653802 hasRelatedWork W1879285787 @default.
- W217653802 hasRelatedWork W2022289327 @default.
- W217653802 hasRelatedWork W2039713508 @default.
- W217653802 hasRelatedWork W2047190988 @default.
- W217653802 hasRelatedWork W2049268697 @default.
- W217653802 hasRelatedWork W2052320154 @default.
- W217653802 hasRelatedWork W2067958410 @default.
- W217653802 hasRelatedWork W2069092878 @default.
- W217653802 hasRelatedWork W2419193380 @default.
- W217653802 hasVolume "1" @default.
- W217653802 isParatext "false" @default.
- W217653802 isRetracted "false" @default.
- W217653802 magId "217653802" @default.
- W217653802 workType "article" @default.