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- W2176615710 abstract "Kidney disease, or lupus nephritis, is the organ involvement that is most closely associated with specific autoantibodies in patients with SLE. The concept of anti-DNA antibodies being instrumental in the pathogenesis of lupus nephritis emerged ~50 years ago, and has been a topic of debate ever since. This article focuses on the description of the renal sub-cellular targets of nephritogenic autoantibodies and offers a counter-point opinion to the article by Pedersen et al. In addition, we provide an overview of some of the mechanisms by which anti-DNA antibodies bind to their renal targets and the pathogenic relevance to clinical nephritis." @default.
- W2176615710 created "2016-06-24" @default.
- W2176615710 creator A5036519472 @default.
- W2176615710 creator A5088498253 @default.
- W2176615710 date "2015-09-01" @default.
- W2176615710 modified "2023-09-27" @default.
- W2176615710 title "The Role of Anti-DNA Antibodies in the Development of Lupus Nephritis: A Complementary, or Alternative, Viewpoint?" @default.
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- W2176615710 doi "https://doi.org/10.1016/j.semnephrol.2015.08.005" @default.
- W2176615710 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4662078" @default.
- W2176615710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26573546" @default.
- W2176615710 hasPublicationYear "2015" @default.
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