FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2176889245> ?p ?o ?g. }

• W2176889245 abstract "Each year, more than four million abdominal surgeries are performed in the US and over 250,000 in England. Acute respiratory failure, a common complication that can affect 30% to 50% of people after upper abdominal surgery, can lead to significant morbidity and mortality. Noninvasive ventilation has been associated with lower rates of tracheal intubation in adults with acute respiratory failure, thus reducing the incidence of complications and mortality. This review compared the effectiveness and safety of noninvasive positive pressure ventilation (NPPV) versus standard oxygen therapy in the treatment of acute respiratory failure after upper abdominal surgery.To assess the effectiveness and safety of noninvasive positive pressure ventilation (NPPV), that is, continuous positive airway pressure (CPAP) or bilevel NPPV, in reducing mortality and the rate of tracheal intubation in adults with acute respiratory failure after upper abdominal surgery, compared to standard therapy (oxygen therapy), and to assess changes in arterial blood gas levels, hospital and intensive care unit (ICU) length of stay, gastric insufflation, and anastomotic leakage.The date of the last search was 12 May 2015. We searched the following databases: the Cochrane Handbook for Systematic Reviews of Interventions (CENTRAL) (2015, Issue 5), MEDLINE (Ovid SP, 1966 to May 2015), EMBASE (Ovid SP, 1974 to May 2015); the physiotherapy evidence database (PEDro) (1999 to May 2015); the Cumulative Index to Nursing and Allied Health Literature (CINAHL, EBSCOhost, 1982 to May 2015), and LILACS (BIREME, 1986 to May 2015). We reviewed reference lists of included studies and contacted experts. We also searched grey literature sources. We checked databases of ongoing trials such as www.controlled-trials.com/ and www.trialscentral.org/. We did not apply language restrictions.We selected randomized or quasi-randomized controlled trials involving adults with acute respiratory failure after upper abdominal surgery who were treated with CPAP or bilevel NPPV with, or without, drug therapy as standard medical care, compared to adults treated with oxygen therapy with, or without, standard medical care.Two authors independently selected and abstracted data from eligible studies using a standardized form. We evaluated study quality by assessing allocation concealment; random sequence generation; incomplete outcome data; blinding of participants, personnel, and outcome assessors; selective reporting; and adherence to the intention-to-treat (ITT) principle.We included two trials involving 269 participants. The participants were mostly men (67%); the mean age was 65 years. The trials were conducted in China and Italy (one was a multicentre trial). Both trials included adults with acute respiratory failure after upper abdominal surgery. We judged both trials at high risk of bias. Compared to oxygen therapy, CPAP or bilevel NPPV may reduce the rate of tracheal intubation (risk ratio (RR) 0.25; 95% confidence interval (CI) 0.08 to 0.83; low quality evidence) with a number needed to treat for an additional beneficial outcome of 11. There was very low quality evidence that the intervention may also reduce ICU length of stay (mean difference (MD) -1.84 days; 95% CI -3.53 to -0.15). We found no differences for mortality (low quality evidence) and hospital length of stay. There was insufficient evidence to be certain that CPAP or NPPV had an effect on anastomotic leakage, pneumonia-related complications, and sepsis or infections. Findings from one trial of 60 participants suggested that bilevel NPPV, compared to oxygen therapy, may improve blood gas levels and blood pH one hour after the intervention (partial pressure of arterial oxygen (PaO2): MD 22.5 mm Hg; 95% CI 17.19 to 27.81; pH: MD 0.06; 95% CI 0.01 to 0.11; partial pressure of arterial carbon dioxide (PCO2) levels (MD -9.8 mm Hg; 95% CI -14.07 to -5.53). The trials included in this systematic review did not present data on the following outcomes that we intended to assess: gastric insufflation, fistulae, pneumothorax, bleeding, skin breakdown, eye irritation, sinus congestion, oronasal drying, and patient-ventilator asynchrony.The findings of this review indicate that CPAP or bilevel NPPV is an effective and safe intervention for the treatment of adults with acute respiratory failure after upper abdominal surgery. However, based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology, the quality of the evidence was low or very low. More good quality studies are needed to confirm these findings." @default.
• W2176889245 created "2016-06-24" @default.
• W2176889245 creator A5011139272 @default.
• W2176889245 creator A5019235416 @default.
• W2176889245 creator A5038149494 @default.
• W2176889245 creator A5066965235 @default.
• W2176889245 date "2015-10-05" @default.
• W2176889245 modified "2023-09-30" @default.
• W2176889245 title "Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery" @default.
• W2176889245 cites W1502462016 @default.
• W2176889245 cites W1517567355 @default.
• W2176889245 cites W1626928636 @default.
• W2176889245 cites W1767305537 @default.
• W2176889245 cites W1782233481 @default.
• W2176889245 cites W1883218415 @default.
• W2176889245 cites W1968042959 @default.
• W2176889245 cites W1981813046 @default.
• W2176889245 cites W1984953928 @default.
• W2176889245 cites W1987188333 @default.
• W2176889245 cites W2002273805 @default.
• W2176889245 cites W2006911249 @default.
• W2176889245 cites W2022338399 @default.
• W2176889245 cites W2027806727 @default.
• W2176889245 cites W2028038216 @default.
• W2176889245 cites W2035171170 @default.
• W2176889245 cites W2037772564 @default.
• W2176889245 cites W2041477760 @default.
• W2176889245 cites W2057925873 @default.
• W2176889245 cites W2059490341 @default.
• W2176889245 cites W2063211595 @default.
• W2176889245 cites W2063998858 @default.
• W2176889245 cites W2080277228 @default.
• W2176889245 cites W2084495062 @default.
• W2176889245 cites W2092369393 @default.
• W2176889245 cites W2102010268 @default.
• W2176889245 cites W2110162455 @default.
• W2176889245 cites W2110307288 @default.
• W2176889245 cites W2111632894 @default.
• W2176889245 cites W2121076911 @default.
• W2176889245 cites W2126051082 @default.
• W2176889245 cites W2126930838 @default.
• W2176889245 cites W2130318815 @default.
• W2176889245 cites W2136024872 @default.
• W2176889245 cites W2142038360 @default.
• W2176889245 cites W2145968378 @default.
• W2176889245 cites W2149263201 @default.
• W2176889245 cites W2149449671 @default.
• W2176889245 cites W2149791050 @default.
• W2176889245 cites W2155566499 @default.
• W2176889245 cites W2156453814 @default.
• W2176889245 cites W2157823046 @default.
• W2176889245 cites W2158425783 @default.
• W2176889245 cites W2159765471 @default.
• W2176889245 cites W2161600342 @default.
• W2176889245 cites W2162258048 @default.
• W2176889245 cites W2163488583 @default.
• W2176889245 cites W2166291113 @default.
• W2176889245 cites W2176889245 @default.
• W2176889245 cites W2394746441 @default.
• W2176889245 cites W2394828170 @default.
• W2176889245 cites W2413751194 @default.
• W2176889245 cites W2415087053 @default.
• W2176889245 cites W4243610187 @default.
• W2176889245 cites W4254997874 @default.
• W2176889245 cites W4367160801 @default.
• W2176889245 cites W1965865050 @default.
• W2176889245 doi "https://doi.org/10.1002/14651858.cd009134.pub2" @default.
• W2176889245 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8080101" @default.
• W2176889245 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26436599" @default.
• W2176889245 hasPublicationYear "2015" @default.
• W2176889245 type Work @default.
• W2176889245 sameAs 2176889245 @default.
• W2176889245 citedByCount "41" @default.
• W2176889245 countsByYear W21768892452015 @default.
• W2176889245 countsByYear W21768892452016 @default.
• W2176889245 countsByYear W21768892452017 @default.
• W2176889245 countsByYear W21768892452018 @default.
• W2176889245 countsByYear W21768892452019 @default.
• W2176889245 countsByYear W21768892452020 @default.
• W2176889245 countsByYear W21768892452021 @default.
• W2176889245 countsByYear W21768892452022 @default.
• W2176889245 countsByYear W21768892452023 @default.
• W2176889245 crossrefType "journal-article" @default.
• W2176889245 hasAuthorship W2176889245A5011139272 @default.
• W2176889245 hasAuthorship W2176889245A5019235416 @default.
• W2176889245 hasAuthorship W2176889245A5038149494 @default.
• W2176889245 hasAuthorship W2176889245A5066965235 @default.
• W2176889245 hasBestOaLocation W21768892451 @default.
• W2176889245 hasConcept C127413603 @default.
• W2176889245 hasConcept C177713679 @default.
• W2176889245 hasConcept C200457457 @default.
• W2176889245 hasConcept C2775867611 @default.
• W2176889245 hasConcept C2776006263 @default.
• W2176889245 hasConcept C2776376669 @default.
• W2176889245 hasConcept C2776888751 @default.
• W2176889245 hasConcept C2777080012 @default.
• W2176889245 hasConcept C2778029997 @default.
• W2176889245 hasConcept C2778716859 @default.
• W2176889245 hasConcept C2780630273 @default.
• W2176889245 hasConcept C42219234 @default.

• next