FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2177097070> ?p ?o ?g. }

• W2177097070 endingPage "3942" @default.
• W2177097070 startingPage "3934" @default.
• W2177097070 abstract "Undercarboxylated osteocalcin (ucOC) modulates insulin secretion and sensitivity in mice, and higher ucOC is associated with lower prevalence of diabetes in men. The influence of ucOC distinct from other markers of bone turnover on incidence of cardiovascular events is unclear. Community-dwelling men aged 70–89 years resident in Perth, Western Australia. Serum total osteocalcin (TOC), N-terminal propeptide of type I collagen (P1NP), and collagen type I C-terminal cross-linked telopeptide (CTX) were measured by immunoassay, and ucOC by hydroxyapatite binding. The ratio ucOC/TOC was calculated. Hospital admissions and deaths from myocardial infarction (MI) and stroke were ascertained. There were 3384 men followed for 7.0 years, during which 293 experienced an MI, 251 stroke, and 2840 neither. In multivariate analyses, higher ratio of ucOC/TOC (expressed as %) was associated with lower incidence of MI (quartiles Q2–4, ≥49% versus Q1,<49%, hazard ratio 0.70, 95% confidence interval = 0.54–0.91), but not of stroke (0.99, 0.73–1.34). Higher P1NP was associated with higher incidence of MI (Q2–4, ≥28.2 μg/L versus Q1, <28.2 μg/L, hazard ratio 1.45, 95% confidence interval = 1.06–1.97), but not of stroke (0.94, 0.70–1.26). CTX was not associated with incident MI or stroke. A reduced proportion of undercarboxylated osteocalcin or higher P1NP are associated with increased incidence of MI. UcOC/TOC ratio and P1NP predict risk of MI but not stroke, in a manner distinct from CTX. Further studies are needed to investigate potential mechanisms by which bone turnover markers related to metabolic risk and to collagen formation could modulate cardiovascular risk." @default.
• W2177097070 created "2016-06-24" @default.
• W2177097070 creator A5012213444 @default.
• W2177097070 creator A5014230293 @default.
• W2177097070 creator A5014800121 @default.
• W2177097070 creator A5043827664 @default.
• W2177097070 creator A5043960846 @default.
• W2177097070 creator A5046761446 @default.
• W2177097070 creator A5054850627 @default.
• W2177097070 creator A5058257161 @default.
• W2177097070 creator A5058775754 @default.
• W2177097070 creator A5058908408 @default.
• W2177097070 creator A5061462083 @default.
• W2177097070 creator A5080721059 @default.
• W2177097070 date "2015-10-01" @default.
• W2177097070 modified "2023-10-11" @default.
• W2177097070 title "Proportion of Undercarboxylated Osteocalcin and Serum P1NP Predict Incidence of Myocardial Infarction in Older Men" @default.
• W2177097070 cites W1802503633 @default.
• W2177097070 cites W1828902039 @default.
• W2177097070 cites W1977628174 @default.
• W2177097070 cites W1980740451 @default.
• W2177097070 cites W1985816699 @default.
• W2177097070 cites W1992382649 @default.
• W2177097070 cites W1995354197 @default.
• W2177097070 cites W1997177472 @default.
• W2177097070 cites W2004115712 @default.
• W2177097070 cites W2004804043 @default.
• W2177097070 cites W2005779589 @default.
• W2177097070 cites W2013943770 @default.
• W2177097070 cites W2014922493 @default.
• W2177097070 cites W2021953996 @default.
• W2177097070 cites W2035397891 @default.
• W2177097070 cites W2038553863 @default.
• W2177097070 cites W2047761422 @default.
• W2177097070 cites W2050441299 @default.
• W2177097070 cites W2050868865 @default.
• W2177097070 cites W2052673490 @default.
• W2177097070 cites W2062671933 @default.
• W2177097070 cites W2068727357 @default.
• W2177097070 cites W2074465767 @default.
• W2177097070 cites W2084685406 @default.
• W2177097070 cites W2091656140 @default.
• W2177097070 cites W2101422068 @default.
• W2177097070 cites W2106118214 @default.
• W2177097070 cites W2107360985 @default.
• W2177097070 cites W2115437802 @default.
• W2177097070 cites W2116427214 @default.
• W2177097070 cites W2121399908 @default.
• W2177097070 cites W2131814354 @default.
• W2177097070 cites W2138326690 @default.
• W2177097070 cites W2141345515 @default.
• W2177097070 cites W2147663252 @default.
• W2177097070 cites W2149112674 @default.
• W2177097070 cites W2158833450 @default.
• W2177097070 cites W2232407802 @default.
• W2177097070 doi "https://doi.org/10.1210/jc.2015-1899" @default.
• W2177097070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26308289" @default.
• W2177097070 hasPublicationYear "2015" @default.
• W2177097070 type Work @default.
• W2177097070 sameAs 2177097070 @default.
• W2177097070 citedByCount "28" @default.
• W2177097070 countsByYear W21770970702017 @default.
• W2177097070 countsByYear W21770970702018 @default.
• W2177097070 countsByYear W21770970702019 @default.
• W2177097070 countsByYear W21770970702020 @default.
• W2177097070 countsByYear W21770970702022 @default.
• W2177097070 countsByYear W21770970702023 @default.
• W2177097070 crossrefType "journal-article" @default.
• W2177097070 hasAuthorship W2177097070A5012213444 @default.
• W2177097070 hasAuthorship W2177097070A5014230293 @default.
• W2177097070 hasAuthorship W2177097070A5014800121 @default.
• W2177097070 hasAuthorship W2177097070A5043827664 @default.
• W2177097070 hasAuthorship W2177097070A5043960846 @default.
• W2177097070 hasAuthorship W2177097070A5046761446 @default.
• W2177097070 hasAuthorship W2177097070A5054850627 @default.
• W2177097070 hasAuthorship W2177097070A5058257161 @default.
• W2177097070 hasAuthorship W2177097070A5058775754 @default.
• W2177097070 hasAuthorship W2177097070A5058908408 @default.
• W2177097070 hasAuthorship W2177097070A5061462083 @default.
• W2177097070 hasAuthorship W2177097070A5080721059 @default.
• W2177097070 hasBestOaLocation W21770970701 @default.
• W2177097070 hasConcept C120665830 @default.
• W2177097070 hasConcept C121332964 @default.
• W2177097070 hasConcept C125870589 @default.
• W2177097070 hasConcept C126322002 @default.
• W2177097070 hasConcept C127413603 @default.
• W2177097070 hasConcept C131075544 @default.
• W2177097070 hasConcept C134018914 @default.
• W2177097070 hasConcept C156957248 @default.
• W2177097070 hasConcept C160160445 @default.
• W2177097070 hasConcept C164705383 @default.
• W2177097070 hasConcept C181199279 @default.
• W2177097070 hasConcept C207103383 @default.
• W2177097070 hasConcept C2780645631 @default.
• W2177097070 hasConcept C44249647 @default.
• W2177097070 hasConcept C500558357 @default.
• W2177097070 hasConcept C55493867 @default.
• W2177097070 hasConcept C61511704 @default.

• next