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• W2177646845 endingPage "1888" @default.
• W2177646845 startingPage "1878" @default.
• W2177646845 abstract "Systemic lupus erythematosus is a remarkable and challenging disorder. Its diversity of clinical features is matched by the complexity of the factors (genetic, hormonal, and environmental) that cause it, and the array of autoantibodies with which it is associated. In this Seminar we reflect on changes in its classification criteria; consider aspects of its more serious clinical expression; and provide a brief review of its aetiopathogenesis, major complications, coping strategies, and conventional treatment. Increased understanding of the cells and molecules involved in the development of the diseases has encouraged the identification of new, better targeted biological approaches to its treatment. The precise role of these newer therapies remains to be established." @default.
• W2177646845 created "2016-06-24" @default.
• W2177646845 creator A5028733874 @default.
• W2177646845 creator A5046695589 @default.
• W2177646845 creator A5065798696 @default.
• W2177646845 date "2014-11-01" @default.
• W2177646845 modified "2023-10-01" @default.
• W2177646845 title "Systemic lupus erythematosus" @default.
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• W2177646845 doi "https://doi.org/10.1016/s0140-6736(14)60128-8" @default.
• W2177646845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24881804" @default.
• W2177646845 hasPublicationYear "2014" @default.

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