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- W2177674943 abstract "Eczema is a frequently encountered dermatologic condition characterized by inflammation resulting in erythema, scaling, induration, and lichenification.The objective of this research was to examine the roll of botanical anti-inflammatories in alleviating the signs and symptoms of mild-to-moderate eczema.A total of 25 subjects 18+ years of age with mild-to-moderate eczema were asked to leave all oral medications and cleansers unchanged substituting the botanical study moisturizer for all topical treatment three times daily for 2 weeks. Investigator, subject, and noninvasive assessments were obtained at baseline and week 2.There was a highly statistically significant (P < 0.001) improvement in investigator-assessed irritation, erythema, desquamation, roughness, dryness, lichenification, itching, and overall skin appearance after 2 weeks of botanical anti-inflammatory moisturizer use. Overall, a 79% reduction in itching was noted. Skin hydration as measured by corneometry increased 44% increase (P < 0.001).The study moisturizer containing the occlusive ingredients of dimethicone and shea butter oil; the humectant ingredients of glycerin, vitamin B, sodium PCA, and sodium hyaluronate; the barrier repair ingredients of ceramide 3, cholesterol, phytosphingosine, ceramide 6 II, and ceramide 1; and the botanical anti-inflammatories allantoin and bisabolol were helpful in reducing the signs and symptoms of mild-to-moderate eczema." @default.
- W2177674943 created "2016-06-24" @default.
- W2177674943 creator A5040567253 @default.
- W2177674943 date "2015-11-24" @default.
- W2177674943 modified "2023-10-06" @default.
- W2177674943 title "A pilot study investigating the efficacy of botanical anti-inflammatory agents in an OTC eczema therapy" @default.
- W2177674943 cites W1988831864 @default.
- W2177674943 cites W4245823973 @default.
- W2177674943 doi "https://doi.org/10.1111/jocd.12199" @default.
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