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- W2177729897 abstract "An improved strategy for the synthesis of 2'-O-methyl-guanosine (6) and 2'-MOE-guanosine (8) is reported. The regioselectivity of the alkylation was attained using a novel silicon-based protecting group, methylene-bis (diisopropyl-silylchloride) (MDPSCl2, 2). The alkylation proceeded in a chemoselective manner using NaHMDS as the base and MeCl or MOE-Br as the appropriate electrophiles." @default.
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- W2177729897 date "2003-10-01" @default.
- W2177729897 modified "2023-10-14" @default.
- W2177729897 title "MDPSCL2: A New Protecting Group for Chemoselective Synthesis of 2′-O-Alkylated Guanosines" @default.
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- W2177729897 doi "https://doi.org/10.1081/ncn-120021959" @default.
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