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- W2177955193 abstract "Information transmission from tumor cells to non-tumor cells in the surrounding microenvironment via microvesicles is a more recently studied form of intercellular signaling that can have a marked impact on the tumor microenvironment. Tumor-derived microvesicles (TMVs) are packed with information including signaling proteins and nucleic acids, and can be taken up by target cells, enabling paracrine signaling. While previous research has focused on how vesicles released from pathologic cells differ from normal cells, the heterogeneity that exists within the TMV population itself is not fully characterized, and only beginning to be appreciated. In this review, we summarize current understanding of the biogenesis and roles of shed TMVs in the tumor microenvironment, and speculate on the consequences for tumor cell signaling in light of the hypothesis that there exists variance within the TMV population. The analysis of differential signaling upon cell-TMV interactions provides insights into potential mechanisms of intercellular communication." @default.
- W2177955193 created "2016-06-24" @default.
- W2177955193 creator A5021978606 @default.
- W2177955193 creator A5055362175 @default.
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- W2177955193 date "2015-10-06" @default.
- W2177955193 modified "2023-09-25" @default.
- W2177955193 title "Tumor-derived microvesicles in the tumor microenvironment: How vesicle heterogeneity can shape the future of a rapidly expanding field" @default.
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- W2177955193 cites W1979751563 @default.
- W2177955193 cites W1980565270 @default.
- W2177955193 cites W1982669563 @default.
- W2177955193 cites W1983881535 @default.
- W2177955193 cites W1984557698 @default.
- W2177955193 cites W1985257726 @default.
- W2177955193 cites W1985576417 @default.
- W2177955193 cites W1990597414 @default.
- W2177955193 cites W1991390602 @default.
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- W2177955193 doi "https://doi.org/10.1002/bies.201500068" @default.
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