FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2178117785> ?p ?o ?g. }

• W2178117785 endingPage "1712" @default.
• W2178117785 startingPage "1702" @default.
• W2178117785 abstract "The roles of chemical compounds in biological systems are now systematically analyzed by high-throughput experimental technologies. To automate the processing and interpretation of large-scale data it is necessary to develop bioinformatics methods to extract information from the chemical structures of these small molecules by considering the interactions and reactions involving proteins and other biological macromolecules. Here we focus on metabolic compounds and present a knowledge-based approach for understanding reactivity and metabolic fate in enzyme-catalyzed reactions in a given organism or group. We first constructed the KEGG RPAIR database containing chemical structure alignments and structure transformation patterns, called RDM patterns, for 7091 reactant pairs (substrate-product pairs) in 5734 known enzyme-catalyzed reactions. A total of 2205 RDM patterns were then categorized based on the KEGG PATHWAY database. The majority of RDM patterns were uniquely or preferentially found in specific classes of pathways, although some RDM patterns, such as those involving phosphorylation, were ubiquitous. The xenobiotics biodegradation pathways contained the most distinct RDM patterns, and we developed a scheme for predicting bacterial biodegradation pathways given chemical structures of, for example, environmental compounds." @default.
• W2178117785 created "2016-06-24" @default.
• W2178117785 creator A5026586100 @default.
• W2178117785 creator A5034753115 @default.
• W2178117785 creator A5038735844 @default.
• W2178117785 creator A5053959379 @default.
• W2178117785 creator A5058022821 @default.
• W2178117785 date "2007-05-22" @default.
• W2178117785 modified "2023-10-10" @default.
• W2178117785 title "Systematic Analysis of Enzyme-Catalyzed Reaction Patterns and Prediction of Microbial Biodegradation Pathways" @default.
• W2178117785 cites W1540649941 @default.
• W2178117785 cites W1551465144 @default.
• W2178117785 cites W1586156432 @default.
• W2178117785 cites W1967861313 @default.
• W2178117785 cites W1979537657 @default.
• W2178117785 cites W1980541971 @default.
• W2178117785 cites W1987062257 @default.
• W2178117785 cites W2034994407 @default.
• W2178117785 cites W2035723736 @default.
• W2178117785 cites W2037236806 @default.
• W2178117785 cites W2044694490 @default.
• W2178117785 cites W2062228347 @default.
• W2178117785 cites W2093164261 @default.
• W2178117785 cites W2108298456 @default.
• W2178117785 cites W2116351296 @default.
• W2178117785 cites W2132040456 @default.
• W2178117785 cites W2150926065 @default.
• W2178117785 cites W2165674132 @default.
• W2178117785 cites W2169026128 @default.
• W2178117785 doi "https://doi.org/10.1021/ci700006f" @default.
• W2178117785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17516640" @default.
• W2178117785 hasPublicationYear "2007" @default.
• W2178117785 type Work @default.
• W2178117785 sameAs 2178117785 @default.
• W2178117785 citedByCount "77" @default.
• W2178117785 countsByYear W21781177852012 @default.
• W2178117785 countsByYear W21781177852013 @default.
• W2178117785 countsByYear W21781177852014 @default.
• W2178117785 countsByYear W21781177852015 @default.
• W2178117785 countsByYear W21781177852016 @default.
• W2178117785 countsByYear W21781177852017 @default.
• W2178117785 countsByYear W21781177852018 @default.
• W2178117785 countsByYear W21781177852019 @default.
• W2178117785 countsByYear W21781177852020 @default.
• W2178117785 countsByYear W21781177852021 @default.
• W2178117785 countsByYear W21781177852022 @default.
• W2178117785 countsByYear W21781177852023 @default.
• W2178117785 crossrefType "journal-article" @default.
• W2178117785 hasAuthorship W2178117785A5026586100 @default.
• W2178117785 hasAuthorship W2178117785A5034753115 @default.
• W2178117785 hasAuthorship W2178117785A5038735844 @default.
• W2178117785 hasAuthorship W2178117785A5053959379 @default.
• W2178117785 hasAuthorship W2178117785A5058022821 @default.
• W2178117785 hasConcept C104317684 @default.
• W2178117785 hasConcept C114965421 @default.
• W2178117785 hasConcept C127413603 @default.
• W2178117785 hasConcept C137858568 @default.
• W2178117785 hasConcept C150194340 @default.
• W2178117785 hasConcept C152724338 @default.
• W2178117785 hasConcept C157021035 @default.
• W2178117785 hasConcept C162317418 @default.
• W2178117785 hasConcept C178790620 @default.
• W2178117785 hasConcept C181199279 @default.
• W2178117785 hasConcept C183696295 @default.
• W2178117785 hasConcept C185592680 @default.
• W2178117785 hasConcept C192989942 @default.
• W2178117785 hasConcept C27881333 @default.
• W2178117785 hasConcept C31258907 @default.
• W2178117785 hasConcept C41008148 @default.
• W2178117785 hasConcept C54355233 @default.
• W2178117785 hasConcept C55493867 @default.
• W2178117785 hasConcept C70721500 @default.
• W2178117785 hasConcept C86803240 @default.
• W2178117785 hasConceptScore W2178117785C104317684 @default.
• W2178117785 hasConceptScore W2178117785C114965421 @default.
• W2178117785 hasConceptScore W2178117785C127413603 @default.
• W2178117785 hasConceptScore W2178117785C137858568 @default.
• W2178117785 hasConceptScore W2178117785C150194340 @default.
• W2178117785 hasConceptScore W2178117785C152724338 @default.
• W2178117785 hasConceptScore W2178117785C157021035 @default.
• W2178117785 hasConceptScore W2178117785C162317418 @default.
• W2178117785 hasConceptScore W2178117785C178790620 @default.
• W2178117785 hasConceptScore W2178117785C181199279 @default.
• W2178117785 hasConceptScore W2178117785C183696295 @default.
• W2178117785 hasConceptScore W2178117785C185592680 @default.
• W2178117785 hasConceptScore W2178117785C192989942 @default.
• W2178117785 hasConceptScore W2178117785C27881333 @default.
• W2178117785 hasConceptScore W2178117785C31258907 @default.
• W2178117785 hasConceptScore W2178117785C41008148 @default.
• W2178117785 hasConceptScore W2178117785C54355233 @default.
• W2178117785 hasConceptScore W2178117785C55493867 @default.
• W2178117785 hasConceptScore W2178117785C70721500 @default.
• W2178117785 hasConceptScore W2178117785C86803240 @default.
• W2178117785 hasIssue "4" @default.
• W2178117785 hasLocation W21781177851 @default.
• W2178117785 hasLocation W21781177852 @default.
• W2178117785 hasOpenAccess W2178117785 @default.
• W2178117785 hasPrimaryLocation W21781177851 @default.

• next